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Merck
CN

793248

多羟基富勒烯,水溶性

别名:

水溶性 C 60, 碳 60 (OH) n, 多羟基富勒烯, 富勒醇

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关于此项目

经验公式(希尔记法):
C60(OH)n · mH2O (n>40, m>8)
NACRES:
NA.23
UNSPSC Code:
12352103
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form

solid

color

light yellow to yellow

solubility

water: soluble >50 mg/mL
DMSO: slightly soluble
methanol: slightly soluble

storage temp.

2-8°C

Quality Level

Application

PHF可以掺入二氧化钛中形成纳米复合材料,可潜在地用于半导体的光催化。其光热和治疗特性可用于基于非侵入性图像的癌症治疗。

General description

多羟基富勒烯(水溶性)(PHF) 是一种功能化富勒烯,也称为富勒烯醇,可用作分子抗氧化剂和纳米颗粒。它是一种无毒的富勒烯,每个分子连接 12-42 个羟基,从而产生水溶性。其结构和羟基的位置取决于培养基的现有 pH 值。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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Yunxiang Sun et al.
Nanoscale, 11(24), 11933-11945 (2019-06-13)
Featuring small sizes, caged structures, low cytotoxicity and the capability to cross biological barriers, fullerene hydroxy derivatives named fullerenols have been explored as nanomedicinal candidates for amyloid inhibition. Understanding the surface chemistry effect of hydroxylation extents and the corresponding amyloid
Yasukazu Saitoh et al.
Journal of photochemistry and photobiology. B, Biology, 102(1), 69-76 (2010-10-15)
Polyhydroxylated fullerenes (fullerenols: C(60)(OH)(n)) are known as the major water-soluble fullerene derivatives which possess particular significance as free radical scavengers or antioxidants in biological systems. Recently, the novel polyhydroxylated fullerene (C(60) (OH)(44)·8H(2)O: SHH-F) was successfully synthesized. In the present study
Synthesis and Biological Activity of Fullerenols with Various Contents of Hydroxyl Groups
Eropkin YM, et al.
Pharmaceutical Chemistry Journal, 47(2), 87-91 (2013)
Facile and scalable synthesis of a highly hydroxylated water-soluble fullerenol as a single nanoparticle
Kokubo K, et al.
Nano Research, 4(2), 204-215 (2011)
Hisae Aoshima et al.
Biocontrol science, 14(2), 69-72 (2009-07-08)
The antimicrobial activities of fullerene C60 and its derivatives against 6 kinds of bacteria and 2 kinds of fungi were evaluated. The tested samples were water-soluble fullerenes (polyvinylpyrrolidone (PVP)/C60, gamma-cyclodextrin (gamma-CD)/C60, and nano-C60) and 3 types of fullerenols (C60(OH)12, C60(OH)36.8H2O

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