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安全信息

793248

Sigma-Aldrich

多羟基富勒烯，水溶性

别名:

水溶性 C 60, 碳 60 (OH) n, 多羟基富勒烯, 富勒醇

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About This Item

经验公式（希尔记法）:
C60(OH)n · mH2O (n>40, m>8)
UNSPSC代码:
12352103
NACRES:
NA.23

表单

solid

质量水平

100

颜色

light yellow to yellow

溶解性

water: soluble >50 mg/mL
DMSO: slightly soluble
methanol: slightly soluble

储存温度

2-8°C

相关类别

一般描述

多羟基富勒烯（水溶性）(PHF) 是一种功能化富勒烯，也称为富勒烯醇，可用作分子抗氧化剂和纳米颗粒。它是一种无毒的富勒烯，每个分子连接 12-42 个羟基，从而产生水溶性。其结构和羟基的位置取决于培养基的现有 pH 值。

应用

PHF可以掺入二氧化钛中形成纳米复合材料，可潜在地用于半导体的光催化。其光热和治疗特性可用于基于非侵入性图像的癌症治疗。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCG7762
MKCC7217

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Yunxiang Sun et al.
Nanoscale, 11(24), 11933-11945 (2019-06-13)
Featuring small sizes, caged structures, low cytotoxicity and the capability to cross biological barriers, fullerene hydroxy derivatives named fullerenols have been explored as nanomedicinal candidates for amyloid inhibition. Understanding the surface chemistry effect of hydroxylation extents and the corresponding amyloid
Yasukazu Saitoh et al.
Journal of photochemistry and photobiology. B, Biology, 102(1), 69-76 (2010-10-15)
Polyhydroxylated fullerenes (fullerenols: C(60)(OH)(n)) are known as the major water-soluble fullerene derivatives which possess particular significance as free radical scavengers or antioxidants in biological systems. Recently, the novel polyhydroxylated fullerene (C(60) (OH)(44)·8H(2)O: SHH-F) was successfully synthesized. In the present study
Synthesis and Biological Activity of Fullerenols with Various Contents of Hydroxyl Groups
Eropkin YM, et al.
Pharmaceutical Chemistry Journal, 47(2), 87-91 (2013)
Facile and scalable synthesis of a highly hydroxylated water-soluble fullerenol as a single nanoparticle
Kokubo K, et al.
Nano Research, 4(2), 204-215 (2011)
Hisae Aoshima et al.
Biocontrol science, 14(2), 69-72 (2009-07-08)
The antimicrobial activities of fullerene C60 and its derivatives against 6 kinds of bacteria and 2 kinds of fungi were evaluated. The tested samples were water-soluble fullerenes (polyvinylpyrrolidone (PVP)/C60, gamma-cyclodextrin (gamma-CD)/C60, and nano-C60) and 3 types of fullerenols (C60(OH)12, C60(OH)36.8H2O
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