752460
聚乙二醇双（胺）
average MN 10,000, cross-linking reagent carboxyl reactive, amine
别名:
O,O′-双(2-氨基乙基)聚乙二醇, 二氨基聚乙二醇, 聚乙二醇二胺, 聚氧乙烯二胺
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关于此项目
线性分子式:
H2N(CH2CH2O)nCH2CH2NH2
化学文摘社编号:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
产品名称
聚乙二醇双（胺）, average Mn 10,000
SMILES string
NCCOCCOCCN
InChI
1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2
InChI key
IWBOPFCKHIJFMS-UHFFFAOYSA-N
form
powder or solid (or chunk(s))
mol wt
average Mn 10,000
reaction suitability
reagent type: cross-linking reagent
reactivity: carboxyl reactive
mp
56-60 °C
Ω-end
amine
α-end
amine
polymer architecture
shape: linear
functionality: homobifunctional
Quality Level
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Application
Polymer for preparing enzyme conjugates soluble in organic solvents†; promising drug carrier†
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Malar A. Azagarsamy, et al.
Material Matters, 7 (2012)
Gaëlle-Anne Cremer et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(6), 437-442 (2006-01-25)
This paper describes the optimization of a synthesis of a difficult sequence related to a 12-mer sequence of a Pan DR epitope (PADRE). Elongation was followed by on-line monitoring of the N(alpha)-Fmoc removal adapted for the batch methodology. Studying the
Phaedria M St Hilaire et al.
Journal of medicinal chemistry, 45(10), 1971-1982 (2002-05-03)
A one-bead-two-compound inhibitor library was synthesized by the split-mix method for the identification of inhibitors of a recombinant cysteine protease from Leishmania mexicana, CPB2.8DeltaCTE. The inhibitor library was composed of octapeptides with a centrally located reduced bond introduced by reductive
Alison G Patrick et al.
Macromolecular bioscience, 10(10), 1184-1193 (2010-07-02)
The design of hydrogels that simultaneously report protease activity and remove excess protease from solution is elucidated. The hydrogels, based on amino-PEGA, combine enzyme-specific peptides flanked with FRET complimented by charged amino acid residues that facilitate protease uptake via short
Emmanuelle Bays et al.
Biomacromolecules, 10(7), 1777-1781 (2009-06-10)
Maleimide end functionalized polymers for site-selective conjugation to free cysteines of proteins were synthesized using reversible addition-fragmentation chain transfer (RAFT) polymerization. A furan-protected maleimide chain transfer agent (CTA) was employed in the RAFT polymerization of poly(ethylene glycol) methyl ether acrylate
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