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Merck
CN

730971

Sigma-Aldrich

2-(二异丙基氨基)甲基丙烯酸乙酯

97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor

别名:

DPA, DPAEMA

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About This Item

经验公式(希尔记法):
C12H23NO2
CAS号:
分子量:
213.32
EC 号:
MDL编号:
UNSPSC代码:
12162002
PubChem化学物质编号:
NACRES:
NA.23

质量水平

方案

97%

表单

liquid

包含

~100 ppm monomethyl ether hydroquinone as inhibitor

折射率

n20/D 1.145

密度

0.900 g/mL at 25 °C

储存温度

2-8°C

SMILES字符串

CC(C)N(CCOC(=O)C(C)=C)C(C)C

InChI

1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3

InChI key

SVYHMICYJHWXIN-UHFFFAOYSA-N

一般描述

2-(二异丙基氨基)甲基丙烯酸乙酯(DPA)是一种甲基丙烯酸类单体,用于制备各种DPA聚合物,包括聚2-(二异丙基氨基)甲基丙烯酸乙酯(PDPA)。PDPA是水溶性聚合物,对pH和温度变化敏感。在低于pKa值(约6.5)的pH下,PDPA会由疏水变为亲水。这种转变是因为它的氨基发生质子化。PDPA聚合物这一独特性质令其十分适合药物递送、基因递送、传感器、表面、膜和色谱等各种各样的应用。

应用

2-(二异丙基氨基)甲基丙烯酸乙酯可用于:
  • 作为单体,用于聚寡乙二醇甲基丙烯酸甲酯(P(OEGMA))和聚2-(二异丙基氨基)甲基丙烯酸乙酯(PDIPAEMA)经RAFT聚合反应合成多重响应性超支化共聚物。获得的聚合物可用于药物递送、基因递送和组织工程。
  • 作为单体合成嵌段共聚物聚乙二醇-b-聚2-(二异丙基氨基)甲基丙烯酸乙酯(PEG-b-PDPAEMA)。这类pH响应型胶束可用于改进细胞内药物递送。DPA单体负责共聚物的pH响应性。

象形图

CorrosionExclamation mark

警示用语:

Danger

危险分类

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

210.0 °F

闪点(°C)

98.9 °C


历史批次信息供参考:

分析证书(COA)

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Fatty fish is the dominant dietary source of n-3 LCPUFAs but it also contains other micronutrients considered important for brain development and function. To our knowledge, the effect of fatty fish intake on cognitive function in adolescents has not been

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