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Merck
CN

729140

聚乙二醇甲醚巯基

average Mn 2,000, chemical modification reagent thiol reactive, methoxy, thiol

别名:

PEG 硫醇, mPEG 硫醇, 甲氧基 PEG 硫醇, 甲氧基聚乙二醇硫醇

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关于此项目

线性分子式:
CH3O(CH2CH2O)nCH2CH2SH
UNSPSC Code:
12162002
NACRES:
NA.23
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产品名称

聚乙二醇甲醚巯基, average Mn 2,000

form

solid

mol wt

average Mn 2,000

reaction suitability

reagent type: chemical modification reagent
reactivity: thiol reactive

mp

50-55 °C

Ω-end

thiol

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

storage temp.

−20°C

Quality Level

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Application

  • Surface modification of polyaniline nanorods with thiol-terminated poly (ethylene oxide):研究用不同分子量的聚乙二醇单甲醚硫醇修饰聚苯胺纳米棒表面,以增强它们的分散性和功能性(DiTullio et al., 2018)。
  • Colorimetric determination of p-phenylenediamine using silver nanoparticles modified with poly (ethylene glycol) methyl ether thiol:用聚乙二醇单甲醚硫醇修饰银纳米颗粒,用于比色测定对苯二胺,说明它的分析化学应用(Lee et al., 2017)。
  • Facile synthesis and self-assembly of amphiphilic polydimethylsiloxane with poly (ethylene glycol) moieties via thiol-ene click reaction:讨论通过巯基-烯点击化学合成与自组装两亲性共聚物,说明聚乙二醇单甲醚硫醇可用于制备多种功能材料(Xia et al., 2015)。
  • Determination of polyethylene glycol end group functionalities by combination of selective reactions and characterization by matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS):研究用基质辅助激光解吸/离子化电离飞行时间质谱法(MALDI-TOF MS)分析聚乙二醇衍生物的端基官能团。聚乙二醇单甲醚硫醇在分析过程中起关键作用(Zhang et al., 2014)。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Michael R Dyson et al.
mAbs, 12(1), 1829335-1829335 (2020-10-27)
The early phase of protein drug development has traditionally focused on target binding properties leading to a desired mode of therapeutic action. As more protein therapeutics pass through the development pipeline; however, it is clear that non-optimal biophysical properties can

商品

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Discover hydrogels, biocompatible materials for drug delivery, tissue engineering, wound care, and 3D bioprinting in innovative biomedical applications

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