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729140

Sigma-Aldrich

聚乙二醇甲醚巯基

average Mn 2,000, chemical modification reagent thiol reactive, methoxy, thiol

别名:

PEG 硫醇, mPEG 硫醇, 甲氧基 PEG 硫醇, 甲氧基聚乙二醇硫醇

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About This Item

线性分子式:
CH3O(CH2CH2O)nCH2CH2SH
UNSPSC代码:
12162002
NACRES:
NA.23

产品名称

聚乙二醇甲醚巯基, average Mn 2,000

表单

solid

质量水平

100

分子量

average Mn 2,000

反应适用性

reagent type: chemical modification reagent
reactivity: thiol reactive

mp

50-55 °C

Ω端

thiol

α端

methoxy

聚合物结构设计

shape: linear
functionality: monofunctional

储存温度

−20°C

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相关类别

应用

  • Surface modification of polyaniline nanorods with thiol-terminated poly (ethylene oxide)：研究用不同分子量的聚乙二醇单甲醚硫醇修饰聚苯胺纳米棒表面，以增强它们的分散性和功能性(DiTullio et al., 2018)。
  • Colorimetric determination of p-phenylenediamine using silver nanoparticles modified with poly (ethylene glycol) methyl ether thiol：用聚乙二醇单甲醚硫醇修饰银纳米颗粒，用于比色测定对苯二胺，说明它的分析化学应用(Lee et al., 2017)。
  • Facile synthesis and self-assembly of amphiphilic polydimethylsiloxane with poly (ethylene glycol) moieties via thiol-ene click reaction：讨论通过巯基-烯点击化学合成与自组装两亲性共聚物，说明聚乙二醇单甲醚硫醇可用于制备多种功能材料(Xia et al., 2015)。
  • Determination of polyethylene glycol end group functionalities by combination of selective reactions and characterization by matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS)：研究用基质辅助激光解吸/离子化电离飞行时间质谱法(MALDI-TOF MS)分析聚乙二醇衍生物的端基官能团。聚乙二醇单甲醚硫醇在分析过程中起关键作用(Zhang et al., 2014)。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
MKCW4630
MKCW3934
MKCS6152
MKCT6481
MKCQ7523

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Michael R Dyson et al.
mAbs, 12(1), 1829335-1829335 (2020-10-27)
The early phase of protein drug development has traditionally focused on target binding properties leading to a desired mode of therapeutic action. As more protein therapeutics pass through the development pipeline; however, it is clear that non-optimal biophysical properties can

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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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