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主要文件

719919

Sigma-Aldrich

Resomer® RG 752 H,聚(D,L-丙交酯-co-乙交酯)

acid terminated, lactide:glycolide 75:25, Mw 4,000-15,000

别名:

RESOMER® RG 752 H, PLGA

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¥1,268.79
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About This Item

线性分子式:
[C3H4O2]x[C2H2O2]y
CAS号:
MDL编号:
UNSPSC代码:
12162002
NACRES:
NA.23

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表单

(Powder or Solid or Chunk(s))

投料比

lactide:glycolide 75:25

分子量

Mw 4,000-15,000

降解时间线

<6 months

杂质

≤0.1% Sulfated Ash (CONF0010 Conforms)

粘度

0.14-0.22 dL/g, 0.5 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

转变温度

Tg 42-46 °C

储存温度

2-8°C

SMILES字符串

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

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此商品
719900719927719862
viscosity

0.14-0.22 dL/g, 0.5 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

viscosity

0.45-0.60 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

viscosity

0.71-1.0 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

viscosity

0.32-0.44 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

form

(Powder or Solid or Chunk(s))

form

amorphous

form

amorphous

form

amorphous

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

feed ratio

lactide:glycolide 75:25

feed ratio

lactide:glycolide 50:50

feed ratio

lactide:glycolide 75:25

feed ratio

lactide:glycolide 65:35

mol wt

Mw 4,000-15,000

mol wt

Mw 38,000-54,000

mol wt

Mw 76,000-115,000

mol wt

Mw 24,000-38,000

一般描述

聚(D, L-丙交酯-co-乙交酯)(PLGA)是一种可生物降解和生物可吸收的聚合物,广泛用于可植入和可注射药物递送系统的配方中。PLGA材料可在体内诱导极小的炎症反应,并降解产生生物相容性乳酸和乙醇酸。

法律信息

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    商品

    Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

    商业生物材料已停滞不前超过30年的时间,因为很少有材料能够成功地从实验台过渡到临床使用。合成型脂族聚酯因其悠久的历史和获得美国食品药品监督管理局(FDA)批准的记录,一直在可吸收生物材料领域占据主导地位。

    Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

    AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

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