所有图片(1)

文件

719900

Resomer^® RG 504 H，聚（D,L-丙交酯-co-乙交酯）

Name: Resomer<SUP>®</SUP> RG 504 H，聚（<SC>D,L</SC>-丙交酯-<I>co</I>-乙交酯）
Brand: ALDRICH

acid terminated, lactide:glycolide 50:50, M_w 38,000-54,000

别名:

RESOMER^® RG 504 H, PLGA

登录查看公司和协议定价

所有图片(1)

About This Item

线性分子式:

[C₃H₄O₂]_x[C₂H₂O₂]_y

CAS号:

26780-50-7

UNSPSC代码:

12162002

NACRES:

NA.23

质量水平

200

形式

amorphous

投料比

lactide:glycolide 50:50

分子量

M_w 38,000-54,000

降解时间线

<3 months

粘度

0.45-0.60 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

转变温度

T_g 46-50 °C

储存温度

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

应用

Resomer^® RG 504 H，聚（D, L-丙交酯-co-乙交酯）可用于制造一种可生物降解的止血装置，用于安全和局部控制释放凝血酶，促进局部血栓形成。

它也可用于制备：包封氧化铜的聚合物纳米球，形成刺激响应的多功能纳米载体。

法律信息

Evonik产品

RESOMER is a registered trademark of Evonik Rohm GmbH

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

输入产品批号来搜索分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

An Orally Administrated Hyaluronan Functionalized Polymeric Hybrid Nanoparticle System for Colon-Specific Drug Delivery.

Niranjan G Kotla et al.

Nanomaterials (Basel, Switzerland), 9(9) (2019-09-05)

There is a pressing clinical need for advanced colon-specific local drug delivery systems that can provide major advantages in treating diseases associated with the colon, such as inflammatory bowel disease (IBD) and colon cancer. A precise colon targeted drug delivery

In-vitro, ex-vivo, and in-vivo evaluation of buprenorphine HCl release from an in situ forming gel of PLGA-PEG-PLGA using N‑methyl‑2‑pyrrolidone as solvent.

Hossein Kamali et al.

Materials science & engineering. C, Materials for biological applications, 96, 561-575 (2019-01-05)

An in situ forming gel (ISFG) of buprenorphine (BP) was prepared using PLGA-PEG-PLGA (triblock) and N‑methyl‑2‑pyrrolidone as solvent for decreasing the initial burst release. Supercritical CO2 method was used for ring opening polymerization of triblock. The optimum formulation of ISFG

Polymeric nanoparticles augment the ocular hypotensive effect of melatonin in rabbits.

Teresa Musumeci et al.

International journal of pharmaceutics, 440(2), 135-140 (2012-10-20)

Melatonin, a neurohormone secreted by the pineal gland, is able to modulate intraocular pressure (IOP). The aim of this study was to generate nanoparticle (NPs) sustained release formulations that allow to extend the pre-corneal residence time of melatonin, thus prolonging

Reduced postoperative chronic pain after tension-free inguinal hernia repair using absorbable sutures: a single-blind randomized clinical trial.

Igor Jeroukhimov et al.

Journal of the American College of Surgeons, 218(1), 102-107 (2013-11-12)

Chronic pain after inguinal hernia repair occurs in 16% to 62% of patients. The underlying mechanism probably involves sensory nerve damage and abnormal healing that might be influenced by the materials chosen for the procedure. We hypothesize that nonabsorbable sutures

Pediatric anophthalmic sockets and orbital implants: outcomes with polymer-coated implants.

Maria Kirzhner et al.

Ophthalmology, 120(6), 1300-1304 (2013-02-13)

To compare wrapped and polymer-coated hydroxyapatite implants in children undergoing primary enucleation with no adjuvant therapies. Retrospective, interventional cohort study. All children undergoing primary enucleation without adjuvant therapies between 1999 and 2009 at a tertiary pediatric cancer hospital. Review and

查看所有相关文献

商品

RESOMER® - Biodegradable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

聚甘油癸二酸酯在组织工程和再生医学的应用

商业生物材料已停滞不前超过30年的时间，因为很少有材料能够成功地从实验台过渡到临床使用。合成型脂族聚酯因其悠久的历史和获得美国食品药品监督管理局（FDA）批准的记录，一直在可吸收生物材料领域占据主导地位。

Poly(Glycerol Sebacate) in Tissue Engineering

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

Biodegradable Polyester Nanoparticle Formation

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

查看所有结果

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

文件

Resomer® RG 504 H，聚（D,L-丙交酯-co-乙交酯）

acid terminated, lactide:glycolide 50:50, Mw 38,000-54,000