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Merck
CN

592684

Sigma-Aldrich

双(二甲基膦)甲烷

97%

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别名:
DMPM
线性分子式:
(CH3)2PCH2P(CH3)2
CAS号:
分子量:
136.11
MDL编号:
UNSPSC代码:
12352001
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

97%

反应适用性

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

折射率

n20/D 1.5060 (lit.)

bp

42 °C/12 mmHg (lit.)

密度

0.86 g/mL at 25 °C (lit.)

官能团

phosphine

SMILES字符串

CP(C)CP(C)C

InChI

1S/C5H14P2/c1-6(2)5-7(3)4/h5H2,1-4H3

InChI key

MRNJHNUEBDGNEL-UHFFFAOYSA-N

应用

Reactant for:
  • Preparation of ruthenium carbonyl hydrido phosphanido diphosphine dinuclear complexes
  • Luminescent face-to-face dinuclear platinum(II) alkynyl phosphine complexes
  • Phosphorus-phosphorus bond and nuclear spin-spin coupling
  • Formation of a catalytic ruthenium(II)-triphos complex

Catalyst for:
  • Asymmetric alkylation of racemic secondary phosphines
  • Palladium-diphosphine catalyzed carbonylation of ethene

象形图

Flame

警示用语:

Danger

危险声明

预防措施声明

危险分类

Pyr. Liq. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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Giovanna Li Petri et al.
British journal of cancer, 123(4), 644-656 (2020-06-05)
Expression of proton-coupled folate transporter (PCFT) is associated with survival of mesothelioma patients treated with pemetrexed, and is reduced by hypoxia, prompting studies to elucidate their correlation. Modulation of glycolytic gene expression was evaluated by PCR arrays in tumour cells
Graziella Cimino-Reale et al.
Journal of hematology & oncology, 10(1), 140-140 (2017-07-19)
Understanding the molecular/cellular underpinnings of diffuse malignant peritoneal mesothelioma (DMPM), a fatal malignancy with limited therapeutic options, is of utmost importance for the fruitful management of the disease. In this context, we previously found that telomerase activity (TA), which accounts
Jana Elias et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(26), 6553-6561 (2019-03-02)
A new boron-boron dehydrocoupling strategy was established, providing convenient access to some diborane(4) compounds starting from simple borane adducts under mild conditions. In contrast to the traditional pathway using a reducing reagent, the reduction from BIII to BII was paradoxically
Sophie Vermersch et al.
Pediatric blood & cancer, 67(6), e28286-e28286 (2020-04-12)
Malignant and multicystic peritoneal mesotheliomas are extremely rare tumors in children, developing from mesothelial cells. No specific guidelines are available at this age. We performed a retrospective analysis of all identified children (< 18-year-old) treated in France from 1987 to 2017 for
Michelandrea De Cesare et al.
Oncotarget, 6(15), 13119-13132 (2015-05-08)
Survivin, which is highly expressed and promotes cell survival in diffuse malignant peritoneal mesothelioma (DMPM), exclusively relies on exportin 1 (XPO1/CRM1) to be shuttled into the cytoplasm and perform its anti-apoptotic function. Here, we explored the efficacy of Selective Inhibitors

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