反应适用性
reaction type: Grignard Reaction
质量水平
浓度
0.5 M in THF
bp
65 °C
密度
0.972 g/mL at 25 °C
储存温度
2-8°C
SMILES字符串
Clc1cc(Cl)cc([Mg]Br)c1
InChI
1S/C6H3Cl2.BrH.Mg/c7-5-2-1-3-6(8)4-5;;/h2-4H;1H;/q;;+1/p-1
InChI key
PWOVECVCCCTJFQ-UHFFFAOYSA-M
应用
3,5-Dichlorophenylmagnesium bromide can be used:
- In one of the key synthetic steps for the preparation of non-alternant polycyclic hydrocarbon named indeno-benzophenalene.
- As a substrate in the synthesis of carboxylic esters by reacting with 2-methyl-4,6-pyrimidyl dicarbonates.
- As a substrate in the synthesis of aryl ketones by reacting with acid chlorides using bis[2-(N,N-dimethylamino)ethyl] ether ligand.
法律信息
Rieke® Metals, Inc. 产品 ®Rieke Metals, Inc. 的注册商标
警示用语:
Danger
危险分类
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
靶器官
Central nervous system, Respiratory system
补充剂危害
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
-6.2 °F - closed cup
闪点(°C)
-21.2 °C - closed cup
法规信息
新产品
A Novel Synthesis of Carboxylic Esters from 2-Methyl-4, 6-pyrimidyl Dicarbonates and Grignard Reagents
Bulletin of the Korean Chemical Society,, 32(5), 1765-1768 (2011)
Addition of Grignard reagents to aryl acid chlorides: an efficient synthesis of aryl ketones
Organic Letters, 7(25), 5593-5595 (2005)
Toward Singlet-Triplet Bistable Nonalternant Kekule? Hydrocarbons: Azulene-to-Naphthalene Rearrangement
Organic Letters, 17(23), 5854-5857 (2015)
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