质量水平
检测方案
98%
mp
53-56 °C (lit.)
SMILES字符串
Ic1cccnc1
InChI
1S/C5H4IN/c6-5-2-1-3-7-4-5/h1-4H
InChI key
XDELKSRGBLWMBA-UHFFFAOYSA-N
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一般描述
3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
应用
3-Iodopyridine may be used to synthesize following pyridine alkaloids:
- theonelladins C
- theonelladins D
- niphatesine C
- xestamine D
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
224.1 °F
闪点(°C)
106.7 °C
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Alina K Feldman et al.
Organic letters, 6(22), 3897-3899 (2004-10-22)
[reaction: see text] 1,4-Disubstituted 1,2,3-triazoles are obtained in excellent yields by a convenient one-pot procedure from a variety of readily available aromatic and aliphatic halides without isolation of potentially unstable organic azide intermediates.
Microwave-assisted solvent-and ligand-free copper-catalysed cross-coupling between halopyridines and nitrogen nucleophiles.
Ernst, R. F.
Green Chemistry, 13(1), 42-45 (2011)
Synthesis of pyridine alkaloids via Pd-catalyzed coupling of 3-iodopyridine, 1, ?-dienes and nitrogen nucleophiles.
Larock RC and Wang Y.
Tetrahedron Letters, 43(1), 21-23 (2002)
Cameron C Bright et al.
Physical chemistry chemical physics : PCCP, 19(46), 31072-31084 (2017-11-21)
Small nitrogen containing heteroaromatics are fundamental building blocks for many biological molecules, including the DNA nucleotides. Pyridine, as a prototypical N-heteroaromatic, has been implicated in the chemical evolution of many extraterrestrial environments, including the atmosphere of Titan. This paper reports
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