One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from in situ generated azides.

One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from in situ generated azides.

Organic letters (2004-10-22)

Alina K Feldman, Benoît Colasson, Valery V Fokin

摘要

[reaction: see text] 1,4-Disubstituted 1,2,3-triazoles are obtained in excellent yields by a convenient one-pot procedure from a variety of readily available aromatic and aliphatic halides without isolation of potentially unstable organic azide intermediates.