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Merck
CN

537284

[2-(甲基丙烯酰基氧基)乙基]二甲基-(3-磺酸丙基)氢氧化铵

95%

别名:

DMAPS, 2-(N-3-Sulfopropyl-N,N-dimethyl ammonium)ethyl methacrylate, N-(3-Sulfopropyl)-N-(methacryloxyethyl)-N,N-dimethylammonium betaine

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关于此项目

线性分子式:
H2C=C(CH3)CO2CH2CH2N(CH3)2(CH2)3SO3
化学文摘社编号:
分子量:
279.35
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
222-860-8
MDL number:
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产品名称

[2-(甲基丙烯酰基氧基)乙基]二甲基-(3-磺酸丙基)氢氧化铵, 95%

InChI key

BCAIDFOKQCVACE-UHFFFAOYSA-N

InChI

1S/C11H21NO5S/c1-10(2)11(13)17-8-7-12(3,4)6-5-9-18(14,15)16/h1,5-9H2,2-4H3

SMILES string

CC(=C)C(=O)OCC[N+](C)(C)CCCS([O-])(=O)=O

assay

95%

mp

150-155 °C (lit.)

Quality Level

Application

由于[2-(甲基丙烯酰基氧基)乙基]二甲基-(3-磺酸丙基)氢氧化铵(DMAPS)具有吸湿性,其每个单体单元含有最多一分子的水。该材料应储存在阴凉干燥处,并且有些反应条件可能需要在聚合前除去水。

General description

[2-(甲基丙烯酰基氧基)乙基]二甲基-(3-磺酸丙基)氢氧化铵(DMAPS)是一种用于合成聚磺基甜菜碱的吸湿性两性离子单体。聚磺基甜菜碱是电中性聚合物,其一个单体单元内含有阳离子和阴离子两种基团,并且具有有趣的性质,例如在盐水溶液中的抗电解质行为、生物相容性和血液相容性。这些性质使聚磺基甜菜碱可用于许多生物医学应用,如药物递送和药物制剂。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

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Chung-Man Lim et al.
Acta biomaterialia, 85, 180-191 (2018-12-26)
To overcome the drawbacks of the UV grafting method, an alternative, thermal grafting process is suggested. The uniform and geometry-independent grafting of zwitterionic polymers on curved cross-linked polyethylene (CLPE), which is used in artificial hip joints, surface was successfully achieved.
Ho Joon Kwon et al.
Acta biomaterialia, 61, 169-179 (2017-08-08)
Introducing antifouling property to biomaterial surfaces has been considered an effective method for preventing the failure of implanted devices. In order to achieve this, the immobilization of zwitterions on biomaterial surfaces has been proven to be an excellent way of
One-pot synthesis of responsive sulfobetaine nanoparticles by RAFT polymerisation: the effect of branching on the UCST cloud point.
Willock H, et al.
Polym. Chem., 5, 1023-1030 (2014)
Cátia G Alves et al.
International journal of pharmaceutics, 582, 119346-119346 (2020-04-22)
New insights about nanomaterials' biodistribution revealed their ability to achieve tumor accumulation by taking advantage from the dynamic vents occurring in tumor's vasculature. This paradigm-shift emphasizes the importance of extending nanomaterials' blood circulation time to enhance their tumor uptake. The
The direct synthesis of sulfobetaine-containing amphiphilic block copolymers and their self-assembly behavior.
Doncom KEB, et al.
Eur. Polymer J., 87, 497-507 (2017)

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