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Merck
CN

529249

Sigma-Aldrich

2-氯-1,3-二甲基氯化咪唑啉

for peptide synthesis

别名:

2-氯-4,5-二氢-1,3-二甲基-1 H -氯化咪唑, DMC

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About This Item

经验公式(希尔记法):
C5H10Cl2N2
CAS号:
分子量:
169.05
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

产品名称

2-氯-1,3-二甲基氯化咪唑啉,

表单

crystalline

质量水平

反应适用性

reaction type: Coupling Reactions

mp

133-140 °C (lit.)

应用

peptide synthesis

官能团

chloro

SMILES字符串

[Cl-].CN1CC[N+](C)=C1Cl

InChI

1S/C5H10ClN2.ClH/c1-7-3-4-8(2)5(7)6;/h3-4H2,1-2H3;1H/q+1;/p-1

InChI key

AEBBXVHGVADBHA-UHFFFAOYSA-M

应用

合成试剂:
标记葡萄糖作为支链寡糖合成的中间体
荧光化学传感器
1,2-二胺作为共激活剂相关精氨酸甲基转移酶 1 的抑制剂
变构葡萄糖激酶激活剂

用于合成以下物质的反应物:
伯胺中的有机叠氮化物

aza-Henry 反应试剂
用于 macroviracin A、cycloviracin B1 和环硅烷全合成的活化剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Alois Fürstner et al.
Journal of the American Chemical Society, 125(43), 13132-13142 (2003-10-23)
The first total synthesis of the antivirally active glycolipid cycloviracin B(1) (1) is described. The approach is based on a two-directional synthesis strategy which constructs the C(2)()-symmetrical macrodiolide core of the target by an efficient template-directed macrodilactonization reaction promoted by
Journal of Organometallic Chemistry, 686, 175-182 (2003)
Yanzi Gou et al.
Journal of polymer science. Part A, Polymer chemistry, 51(12), 2588-2597 (2013-06-14)
Synthetic glycopolymers are important natural oligosaccharides mimics for many biological applications. To develop glycopolymeric drugs and therapeutic agents, factors that control the receptor-ligand interaction need to be investigated. A library of well-defined glycopolymers has been prepared by the combination of
Shunya Takahashi et al.
The Journal of organic chemistry, 69(13), 4509-4515 (2004-06-19)
The C(2)-symmetric macrodiolide core 2 of an antiviral agent, macroviracin A (1), was constructed in a single step by the intermolecular macrodimerization of C(22)-hydroxy carboxylic acid 3 with 2-chloro-1,3-dimethylimidazolinium chloride and DMAP in the presence of sodium hydride (NaH). The
Shonoi A Ming et al.
Glycobiology, 28(2), 100-107 (2017-12-12)
Neisseria meningitidis Group X is an emerging cause of bacterial meningitis in Sub-Saharan Africa. The capsular polysaccharide of Group X is a homopolymer of N-acetylglucosamine α(1-4) phosphate and is a vaccine target for prevention of disease associated with this meningococcal

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N-Acylimidazoles and carbonylimidazoles are reactive intermediates used for amino compound acylation, surpassing DCC as coupling reagents.

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