推荐产品
质量水平
方案
97%
mp
240-244 °C (lit.)
官能团
phenyl
SMILES字符串
O=C1NN=C(c2ccccc2)c3ccccc13
InChI
1S/C14H10N2O/c17-14-12-9-5-4-8-11(12)13(15-16-14)10-6-2-1-3-7-10/h1-9H,(H,16,17)
InChI key
XCJLBNVENUPHEA-UHFFFAOYSA-N
一般描述
4-Phenyl-1-(2H)-phthalazinone can be prepared from hydrazine sulphate and sodium hydroxide.
应用
4-Phenyl-1-(2H)-phthalazinone may be used in the synthesis of 2-chloro-N-(unsubstituted/substitutedphenyl) acetamide.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Drug metabolism and disposition: the biological fate of chemicals, 42(8), 1326-1333 (2014-06-11)
Lenvatinib is a multityrosine kinase inhibitor that inhibits vascular endothelial growth factor receptors, and is being developed as an anticancer drug. P450s are involved in one of the elimination pathways of lenvatinib, and mono-oxidized metabolites, such as N-oxide (M3) and
European journal of medicinal chemistry, 89, 549-560 (2014-12-03)
A novel series of N-substituted-4-phenylphthalazin-1-ones 14a-g bearing different anilines at the N-2 of phthalazin-1-one scaffold via acetyl-flexible linker was designed and synthesized for the development of potential anticancer agents. Compounds 19a-g were synthesized by insertion of methylene (CH2) bridge at
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