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质量水平
方案
96%
mp
92-96 °C (lit.)
官能团
bromo
SMILES字符串
Brc1ccc2cc[nH]c2c1
InChI
1S/C8H6BrN/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H
InChI key
MAWGHOPSCKCTPA-UHFFFAOYSA-N
一般描述
6-溴吲哚是一种吲哚衍生物。它可与2-(4-氟苯基)乙基哌嗪进行钯催化反应得到羰基化产物。
应用
6-取代吲哚化学中必需的起始剂。
6-溴吲哚可被用于合成:
- 6-烷基硫代吲哚
- 3-乙酰氧基-6-溴吲哚
- 6,6′-二溴靛蓝(泰尔紫)
- 6-酰基吲哚
- 6-溴吲哚-1-羧酸叔丁酯
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Palladium-catalyzed carbonylation of haloindoles: No need for protecting groups.
Organic Letters, 6(1), 7-10 (2004)
A facile synthesis of Tyrian purple based on a biosynthetic pathway.
Fisheries Science (Tokyo, Japan), 67(4), 726-729 (2001)
Journal of the American Chemical Society, 126(16), 5068-5069 (2004-04-22)
The first total synthesis of racemic perophoramidine is described. The key step features the highly stereoselective introduction of the vicinial quaternary centers via base-promoted carbon-carbon bond formation between a 3-alkylindole and a 3-bromo-3-alkylindolin-2-one. This transformation presumably proceeds through a conjugate
Efficient synthesis of 5-and 6-tributylstannylindoles and their reactivity with acid chlorides in the Stille coupling reaction.
Tetrahedron Letters, 48(33), 5751-5753 (2007)
Synthesis of N-protected Nortopsentins B and D.
ARKIVOC (Gainesville, FL, United States), 1, 393-401 (2000)
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