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质量水平
方案
96%
表单
solid
mp
41-44 °C (lit.)
官能团
bromo
SMILES字符串
Brc1cccc2cc[nH]c12
InChI
1S/C8H6BrN/c9-7-3-1-2-6-4-5-10-8(6)7/h1-5,10H
InChI key
RDSVSEFWZUWZHW-UHFFFAOYSA-N
一般描述
7-Bromoindole is a 7-substituted indole derivative. Its synthesis from 7-bromoindole-2-carboxylic acid has been reported. It has been reported to reduce the production of staphyloxanthin in Staphylococcus aureus.
应用
7-Bromoindole may be used in the synthesis of the following:
- indole
- dyestuffs
- 8-bromocarboline
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Total synthesis of indoles from Tricholoma species via Bartoli/heteroaryl radical methodologies.
The Journal of organic chemistry, 66(2), 638-641 (2001-06-30)
The structure of monobrominated ethyl indole-3-carboxylate and the preparation of 7-bromoindole.
Canadian Journal of Chemistry, 38(9), 1467-1471 (1960)
Tetrahedron letters, 53(5), 477-479 (2012-05-01)
A novel MCAP-cycloaddition sequence has been applied to the facile synthesis of β-carboline intermediates to gain rapid access to novel derivatives of yohimbine-like and corynanthe-like compounds that may be easily diversified by cross-coupling reactions and N-derivatizations to generate small compound
Applied microbiology and biotechnology, 97(10), 4543-4552 (2013-01-16)
Human pathogens can readily develop drug resistance due to the long-term use of antibiotics that mostly inhibit bacterial growth. Unlike antibiotics, antivirulence compounds diminish bacterial virulence without affecting cell viability and thus, may not lead to drug resistance. Staphylococcus aureus
Letters in applied microbiology, 41(2), 163-168 (2005-07-22)
To establish multicomponent phenol hydroxylases (mPHs) as novel biocatalysts for producing dyestuffs and hydroxyindoles such as 7-hydroxyindole (7-HI) from indole and its derivatives. We have isolated Pseudomonas sp. KL33, which possesses a phenol degradation pathway similar to that found in
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