推荐产品
检测方案
99%
折射率
n20/D 1.5325 (lit.)
bp
162-164 °C/750 mmHg (lit.)
密度
1.71 g/mL at 25 °C (lit.)
SMILES字符串
Fc1ccc(Br)cn1
InChI
1S/C5H3BrFN/c6-4-1-2-5(7)8-3-4/h1-3H
InChI key
MYUQKYGWKHTRPG-UHFFFAOYSA-N
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警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
163.4 °F
闪点(°C)
73 °C
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Andrew Sutherland et al.
The Journal of organic chemistry, 68(6), 2475-2478 (2003-03-15)
Two racemic fluoropyridine analogues 4 and 5 of the potent nicotinic agonist UB-165 have been synthesized. Halogenated pyridines 7 and 12 provided the organometallic reagents needed for the Negishi and Suzuki coupling reactions used for the preparation of 4 and
Andrew Sutherland et al.
The Journal of organic chemistry, 68(8), 3352-3355 (2003-04-12)
5-bromo-2-fluoro-3-pyridylboronic acid (3) was prepared in high yield by ortho-lithiation of 5-bromo-2-fluoropyridine (1), followed by reaction with trimethylborate. Suzuki reaction of 3 with a range of aryl iodides gave 3-monosubstituted 5-bromo-2-fluoropyridines 4 in excellent yields. A second Suzuki reaction utilizing
Aromatic fluorine compounds. XI. Replacement of chlorine by fluorine in halopyridines.
Finger GC, et al.
The Journal of Organic Chemistry, 28(6), 1666-1668 (1963)
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