所有图片(4)
About This Item
经验公式（希尔记法）:
C5H6BNO2
CAS号:
分子量:
122.92
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.22
推荐产品
质量水平
方案
≥95.0%
表单
solid
mp
>300 °C (lit.)
SMILES字符串
OB(O)c1cccnc1
InChI
1S/C5H6BNO2/c8-6(9)5-2-1-3-7-4-5/h1-4,8-9H
InChI key
ABMYEXAYWZJVOV-UHFFFAOYSA-N
应用
3-吡啶基硼酸可用作以下反应中的试剂：
它也可用于制备：
- 不含磷的Suzuki-Miyaura交叉偶联反应
- 区域选择性Suzuki-Miyaura偶联和串联钯催化的分子内氨基羰基化和环化
- 乙酰丙酮铜催化的N-芳基化反应
- 铜介导的富电子苯的氰化和区域选择性氰化反应
它也可用于制备：
- 通过Suzuki偶联反应制备新型线性聚（苯基吡啶基）链
- 低聚吡啶基折叠体，作为α-螺旋扭曲结构的模拟物
- 许多非常重要的治疗性酶和激酶抑制剂以及受体拮抗剂
- 通过Suzuki偶联反应与二溴吡啶胺化物反应生成吡啶取代的吡啶N-（2′-叠氮基）胺化物。
其他说明
含不定量的酸酐
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Jana Sopkova-de Oliveira Santos et al.
Journal of chemical information and modeling, 52(2), 429-439 (2011-12-27)
Protein-protein interactions are central to many biological processes, from intracellular communication to cytoskeleton assembly, and therefore represent an important class of targets for new therapeutics. The most common secondary structure in natural proteins is an α-helix. Small molecules seem to
Regioselective Suzuki coupling on pyridinium N-(3,5-dibromoheteroar-2-yl)aminides
M. Jose R, et al.
Tetrahedron Letters, 47, 36, 6457-6460 (2006)
Synthesis of new linear poly(phenylpyridyl) chains
Perato, S.; et al.
Tetrahedron, 68, 1910-1917 (2012)
Justin I Montgomery et al.
Journal of medicinal chemistry, 55(4), 1662-1670 (2012-01-20)
The synthesis and biological activity of a new series of LpxC inhibitors represented by pyridone methylsulfone hydroxamate 2a is presented. Members of this series have improved solubility and free fraction when compared to compounds in the previously described biphenyl methylsulfone
Brian C Shook et al.
Journal of medicinal chemistry, 55(3), 1402-1417 (2012-01-14)
The design and characterization of two, dual adenosine A(2A)/A(1) receptor antagonists in several animal models of Parkinson's disease is described. Compound 1 was previously reported as a potential treatment for Parkinson's disease. Further characterization of 1 revealed that it was
商品
Suzuki-Miyaura cross-coupling reaction is extensively used in organic chemistry, polymer science, and pharmaceutical industries.
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