所有图片(1)
别名:
(Trifluoromethyl)trimethylsilane, Ruppert 试剂, TFMTMS
线性分子式:
(CH3)3SiCF3
CAS号:
分子量:
142.19
Beilstein:
4241868
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22
推荐产品
质量水平
检测方案
99%
反应适用性
reaction type: C-C Bond Formation
bp
54-55 °C (lit.)
密度
0.962 g/mL at 20 °C (lit.)
储存温度
2-8°C
SMILES字符串
C[Si](C)(C)C(F)(F)F
InChI
1S/C4H9F3Si/c1-8(2,3)4(5,6)7/h1-3H3
InChI key
MWKJTNBSKNUMFN-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
应用
三甲基（三氟甲基）硅烷可以在以下过程中用作三氟甲基化剂：
- 将 N-(叔-丁基亚磺酰基）-亚胺转化为三氟甲基化胺
- 将反式-烯酮转化为反式-α-三氟甲基甲硅烷基醚
- 偶氮甲亚胺的三氟甲基化
- 将H-膦酸酯转化为CF3-膦酸酯
- 三氟甲基通过亲核加成转化成醛和酮。
警示用语：
Danger
危险声明
危险分类
Flam. Liq. 2 - Water-react 2
WGK
WGK 3
闪点(°F)
1.4 °F
闪点(°C)
-17 °C
个人防护装备
Eyeshields, Faceshields, Gloves
法规信息
危险化学品
Craig P Johnston et al.
Journal of the American Chemical Society, 140(35), 11112-11124 (2018-08-07)
The mechanism of CF3 transfer from R3SiCF3 (R = Me, Et, iPr) to ketones and aldehydes, initiated by M+X- (<0.004 to 10 mol %), has been investigated by analysis of kinetics (variable-ratio stopped-flow NMR and IR), 13C/2H KIEs, LFER, addition
CsF-catalyzed nucleophilic trifluoromethylation of trans-enones with trimethyl (trifluoromethyl) silane: A facile synthesis of trans-?-trifluoromethyl allylic alcohols.
Singh R P, et al.
Organic Letters, 1(7), 1047-1049 (1999)
Copper-catalyzed aerobic oxidative trifluoromethylation of H-phosphonates using trimethyl (trifluoromethyl) silane
Chu L, et al.
Synthesis, 44(10), 1521-1525 (2012)
Peter T Kaplan et al.
Beilstein journal of organic chemistry, 13, 2297-2303 (2017-11-29)
A number of copper reagents were compared for their effectiveness in trifluoromethylating 4-iodobiphenyl, 4-iodotoluene, and 2-iodotoluene. Yields over time were plotted in order to refine our understanding of each reagent performance, identify any bottlenecks, and provide more insight into the
G K Surya Prakash et al.
The Journal of organic chemistry, 71(18), 6806-6813 (2006-08-26)
Organofluorine compounds are becoming increasingly important in different fields, such as material science, agro chemistry, and the pharmaceutical industry. Nucleophilic trifluoromethylation is one of the widely used methods to incorporate a trifluoromethyl moiety into organic molecules. We have carried out
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门