推荐产品
质量水平
方案
≥95.0%
杂质
<10% water
mp
105 °C (dec.) (lit.)
SMILES字符串
Cc1cccc(C)c1B(O)O
InChI
1S/C8H11BO2/c1-6-4-3-5-7(2)8(6)9(10)11/h3-5,10-11H,1-2H3
InChI key
ZXDTWWZIHJEZOG-UHFFFAOYSA-N
应用
Reagent used for
Reagent used in Prepration of
- Palladium catalyzed Suzuki-Miyaura coupling reactions
- One-pot ipso-nitration of arylboronic acids including broader substrate scope of heterocycles and functional groups
- Nickel-Catalyzed Cross-Coupling of Chromene Acetals and Boronic Acids
- Visible-light initiated aerobic oxidative hydroxylation catalyzed by Ru-complex
- Rhodium(I)-catalyzed 1,4-addition reactions
- Pd-catalyzed homocouplings
- Expanded scope of Cu assisted Suzuki-Miyaura coupling reactions including aryl chlorides and polyhalo aryl boronates
Reagent used in Prepration of
- Orally bioavialable G Protein-Coupled Receptor 40 agonists for diabetes treatment
- Solid phase synthesis and antitumor structure-activity relationship of Smac triazoloprolines and biarylalanines tetrapeptide libraries
- Protein Kinase inhibitors
其他说明
含不定量的酸酐
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Satoshi Mikami et al.
Journal of medicinal chemistry, 55(8), 3756-3776 (2012-03-21)
As part of a program to identify potent GPR40 agonists with drug-like properties suitable for clinical development, the incorporation of polar substituents was explored with the intention of decreasing the lipophilicity of our recently disclosed phenylpropanoic acid derivative 1. This
Thomas J A Graham et al.
Organic letters, 14(6), 1616-1619 (2012-03-06)
A modular and highly efficient protocol for the synthesis of 2-aryl- and heteroaryl-2H-chromenes is described. Under base-free conditions, readily accessible 2-ethoxy-2H-chromenes undergo C(sp(3))-O activation and C(sp(3))-C bond formation in the presence of an inexpensive nickel catalyst and boronic acids. This
Santos-Filho, E. F.; et al.
Tetrahedron Letters, 52, 5288-5288 (2011)
Rhodium(I)-catalyzed 1,4-addition of arylboronic acids to acrylic acid in water: one-step preparation of 3-arylpropionic acids
Vautravers, N. R.; Breit, B.
Synlett, 17, 2517-2520 (2011)
Sebastian T Le Quement et al.
ACS combinatorial science, 13(6), 667-675 (2011-09-13)
Apoptotic induction mechanisms are of crucial importance for the general homeostasis of multicellular organisms. In cancer the apoptotic pathways are downregulated, which, at least partly, is due to an abundance of inhibitors of apoptosis proteins (IAPs) that block the apoptotic
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