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Merck
CN

470791

Sigma-Aldrich

2,6-二氟苯硼酸

98%

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About This Item

线性分子式:
F2C6H3B(OH)2
分子量:
157.91
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

mp

147-149 °C (lit.)

官能团

fluoro

SMILES字符串

OB(O)c1c(F)cccc1F

InChI

1S/C6H5BF2O2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,10-11H

InChI key

DBZAICSEFBVFHL-UHFFFAOYSA-N

应用

2,6-Difluorophenylboronic acid can be used:
  • As a substrate in the model reaction of Suzuki–Miyaura coupling with 4-chloro-3-methylanisole.
  • To prepare 4-bromo-2,3′,5′,6-tetrafluorobiphenyl, a key intermediate for the synthesis of 2,6-difluorinated oligophenyls applicable in organic semiconductors.
  • To prepare ethyl 4-(2,6-difluorophenyl)nicotinate, a key intermediate for the synthesis of 4-phenyl pyridine based potent TGR5 agonists.

其他说明

含有不定量的酸酐

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Design and preparation of new palladium precatalysts for C-C and C-N cross-coupling reactions
Bruno NC, et al.
Chemical Science, 4(3), 916-920 (2013)
Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold
Zhu J, et al.
European Journal of Medicinal Chemistry, 69, 55-68 (2013)
Enhancing charge mobilities in selectively fluorinated oligophenyl organic semiconductors: a design approach based on experimental and computational perspectives
Maiti B, et al.
Journal of Material Chemistry C, 7(13), 3881-3888 (2019)

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