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质量水平
反应适用性
reaction type: Grignard Reaction
浓度
1.0 M in THF
沸点
65-67 °C
密度
1.002 g/mL at 25 °C
SMILES字符串
Cc1ccc([Mg]Br)cc1
InChI
1S/C7H7.BrH.Mg/c1-7-5-3-2-4-6-7;;/h3-6H,1H3;1H;/q;;+1/p-1
InChI key
ZRJNGFJIBZKXTP-UHFFFAOYSA-M
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应用
对甲苯基溴化镁是一种常用的格氏试剂。它也可以用于多种交叉偶联反应中。
警示用语:
Danger
危险分类
Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
靶器官
Central nervous system, Respiratory system
补充剂危害
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
1.4 °F
闪点(°C)
-17 °C
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Dinuclear Iron Complex-Catalyzed Cross-Coupling of Primary Alkyl Fluorides with Aryl Grignard Reagents.
Mo Z, et al.
Organometallics, 31(18), 6518-6521 (2012)
Palladium-catalyzed cross coupling of Grignard reagents with in situ-derived enol phosphates.
Miller JA
Tetrahedron Letters, 43(39), 7111-7114 (2002)
Palladium-and Nickel-Catalyzed Kumada Cross-Coupling Reactions of gem-Difluoroalkenes and Monofluoroalkenes with Grignard Reagents.
Dai W
The Journal of Organic Chemistry, 79(21), 10537-10546 (2014)
Takuji Hatakeyama et al.
Journal of the American Chemical Society, 131(33), 11949-11963 (2009-07-31)
Combinations of N-heterocyclic carbenes (NHCs) and fluoride salts of the iron-group metals (Fe, Co, and Ni) have been shown to be excellent catalysts for the cross-coupling reactions of aryl Grignard reagents (Ar(1)MgBr) with aryl and heteroaryl halides (Ar(2)X) to give
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