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Merck
CN

437891

Sigma-Aldrich

O,O-二甲基磷酰氯

96%

别名:

二甲基磷酰氯

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About This Item

线性分子式:
(CH3O)2P(O)Cl
CAS号:
分子量:
144.49
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

96%

形式

liquid

折射率

n20/D 1.413 (lit.)

bp

80 °C/25 mmHg (lit.)

密度

1.34 g/mL at 25 °C (lit.)

SMILES字符串

COP(Cl)(=O)OC

InChI

1S/C2H6ClO3P/c1-5-7(3,4)6-2/h1-2H3

InChI key

NGFFLHMFSINFGB-UHFFFAOYSA-N

应用

氯磷酸二甲酯可用于通过与氰基丙酮酸乙酯的烯醇钾盐反应制备 ( E )-3-氰基磷酸烯醇丙酮酸。可用于合成 2-花生四烯酸甘油醚的单磷酸酯和二磷酸酯。

象形图

Skull and crossbonesCorrosion

警示用语:

Danger

危险分类

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B

WGK

WGK 3

闪点(°F)

235.4 °F

闪点(°C)

113 °C

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Juha Juntunen et al.
Journal of medicinal chemistry, 46(23), 5083-5086 (2003-10-31)
The poor aqueous solubility of 2-arachidonyl glyceryl ether (noladin ether) 2 hinders both pharmacological studies and pharmaceutical development. The synthesized mono- and diphosphate esters of noladin ether (4 and 6) considerably increased the aqueous solubility of noladin ether (>40000-fold), showed
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Langmuir : the ACS journal of surfaces and colloids, 28(30), 10962-10967 (2012-07-12)
The fundamental interactions of dimethyl methylphosphonate (DMMP) and dimethyl chlorophosphate (DMCP) on amorphous silica nanoparticles have been investigated with transmission infrared spectroscopy and temperature-programmed desorption (TPD). DMMP and DMCP both adsorb molecularly to silica through the formation of hydrogen bonds
P Wirsching et al.
Biochemistry, 24(26), 7602-7606 (1985-12-17)
(E)-3-Cyanophosphoenolpyruvate has been synthesized by reacting dimethyl chlorophosphate with the potassium enolate of ethyl cyanopyruvate. The resulting trialkyl ester was deesterified with bromotrimethylsilane followed by potassium hydroxide. Subsequent treatment with Dowex-50-H+ resin and cyclohexylamine afforded the tricyclohexylammonium salt; only the
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ACS applied materials & interfaces, 11(8), 7686-7694 (2019-02-16)
Quorum sensing (QS) inhibitor-based therapy is an attractive strategy to inhibit bacterial biofilm formation without excessive induction of antibiotic resistance. Thus, we designed Ca2+-binding poly(lactide- co-glycolide) (PLGA) microparticles that can maintain a sufficient concentration of QS inhibitors around hydroxyapatite (HA)

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