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等级
technical grade
质量水平
方案
90%
表单
solid
mp
99-103 °C (lit.)
官能团
amine
fluoro
SMILES字符串
Cl.NCCF
InChI
1S/C2H6FN.ClH/c3-1-2-4;/h1-2,4H2;1H
InChI key
YRRZGBOZBIVMJT-UHFFFAOYSA-N
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一般描述
2-Fluoroethylamine hydrochloride is a fluorinated alkylammonium salt. Studies suggest that adding a fluorine atom to it leads to double gauche effect in the resulting 2,2-difluoroethylamine chloride. Microwave spectral studies for 2-fluoroethylamine has been conducted.
应用
2-Fluoroethylamine hydrochloride may be used in the synthesis of the following:
- 2-fluoroethylisocyanate
- 1,3-bis-(2-fluoroethyl) urea (BFU)
- N-2-fluoroethylmaleimide
- [Cu4(O)(Ln)2(CH3COO)4] where HL= 4-methyl-2,6-bis(2-fluoroethyliminomethyl) phenol
- 1-O-(4-(2-fluoroethyl-carbamoyloxymethyl)-2-nitrophenyl)-O-β-D-glucopyronuronate (FEAnGA)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Development of a new thiol site-specific prosthetic group and its conjugation with [Cys40]-exendin-4 for in vivo targeting of insulinomas.
Yue X, et al.
Bioconjugate Chemistry, 24(7), 1191-1200 (2013)
Conformational analysis of 2, 2-difluoroethylamine hydrochloride: double gauche effect.
Silla JM, et al.
Beilstein Journal of Organic Chemistry, 10(1), 877-882 (2014)
Inês F Antunes et al.
Bioconjugate chemistry, 21(5), 911-920 (2010-04-27)
To increase the therapeutic index of chemotherapeutic drugs, prodrugs have been investigated as anticancer agents, as they may present fewer cytotoxic side effects than conventional cytotoxic drugs, while therapeutic efficacy is maintained or even increased. Extracellular beta-glucuronidase (beta-GUS) in the
Synthesis of 18F-labelled 2-fluoroethyl-nitrosoureas.
Farrokhzad S, et al.
Canadian Journal of Chemistry, 62(11), 2107-2112 (1984)
Tetranuclear copper (II)-Schiff-base complexes as active catalysts for oxidation of cyclohexane and toluene.
Roy P and Manassero M.
Dalton Transactions, 39(6), 1539-1545 (2010)
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