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Merck
CN

409472

Sigma-Aldrich

N-[(3-(二甲氨基)丙基]甲基丙烯酰胺

99%, contains MEHQ as inhibitor

别名:

N ,N -二甲氨基丙基甲基丙烯酰胺, N -[3-(N ,N -二甲氨基)丙基]甲基丙烯酰胺

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About This Item

线性分子式:
H2C=C(CH3)CONH(CH2)3N(CH3)2
CAS号:
分子量:
170.25
EC 号:
MDL编号:
UNSPSC代码:
12162002
PubChem化学物质编号:
NACRES:
NA.23

质量水平

描述

contains: ~650ppm MEHQ as inhibitor

方案

99%

表单

viscous liquid

折射率

n20/D 1.479 (lit.)

沸点

134 °C/2 mmHg (lit.)

密度

0.94 g/mL at 25 °C (lit.)

SMILES字符串

CN(C)CCCNC(=O)C(C)=C

InChI

1S/C9H18N2O/c1-8(2)9(12)10-6-5-7-11(3)4/h1,5-7H2,2-4H3,(H,10,12)

InChI key

GDFCSMCGLZFNFY-UHFFFAOYSA-N

一般描述

N-[3-(二甲氨基)丙基]甲基丙烯酰胺(DMAPMA) 是一种水溶性甲基丙烯酰胺单体。它是高活性的,可以进行自由基聚合和交联反应。该 (-N(CH3)2)的存在使所得聚合物具有pH 响应性和亲水性。这种多功能 单体可用于药物输送系统、基因输送、反应材料、 生物相容性涂层、粘合剂和生物医学工程。

应用

N-[3-(二甲基胺)丙基]甲基丙烯酰胺可用于:



  • 作为单体合成自愈pH应P(DMAPMA-stat-DAA)水凝胶,用于药物递送应用。
  • 作为一种阳离子单体,由于其能够与核酸复合并促进其在细胞内的传递而成为基因传递载体。
  • 制备用于3D打印的氧化铁纳米颗粒配方。这些铁墨水用于打印磁性设备,用于生物成像的MRI造影剂和靶向药物输送系统。
  • 制备一种无毒的微藻合成絮凝剂。

  • Glucose-containing diblock polycations exhibit molecular weight, charge, and cell-type dependence for pDNA delivery.: This study investigates the use of glucose-containing diblock polycations, including N-[3-(Dimethylamino)propyl]methacrylamide, in pDNA delivery systems. The research demonstrates that the efficiency of pDNA delivery is influenced by the molecular weight and charge of the polycations, as well as the type of cell used. This highlights the potential for tailored gene delivery applications in different cell types, emphasizing the role of N-[3-(Dimethylamino)propyl]methacrylamide in creating biocompatible and effective delivery vectors (Wu et al., 2014).

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

预防措施声明

危险分类

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

264.2 °F - closed cup

闪点(°C)

129 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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John E Blume et al.
Nature communications, 11(1), 3662-3662 (2020-07-24)
Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma proteome. Here we report a highly parallel protein quantitation platform integrating nanoparticle (NP) protein coronas with liquid chromatography-mass spectrometry for efficient proteomic profiling. A protein corona is a
Kathryn L Morrissey et al.
Journal of colloid and interface science, 567, 316-327 (2020-02-18)
Flocculation performance using polyelectrolytes is influenced by critical design parameters including molecular weight, amount and sign of the ionic charge, and polymer architecture. It is expected that systematic variation of these characteristics will impact not only flocculation efficiency (FE) achieved
Merve Yaşar et al.
Journal of biomaterials science. Polymer edition, 31(16), 2044-2059 (2020-07-10)
The fabrication of molecularly imprinted nanoparticles (MIP-NPs) specific for myoglobin by using thiol-ene photopolymerization in miniemulsion was described. Allyl derivatives of phenylalanine as a functional monomer was synthesized and copolymerized with acrylic monomers via miniemulsion polymerization to produce NIP-NPs with

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