推荐产品
质量水平
产品线
ReagentPlus®
方案
99%
表单
powder
旋光性
[α]20/D +59°, c = 2 in ethanol
mp
49-53 °C (lit.)
官能团
carboxylic acid
SMILES字符串
CC(C)Cc1ccc(cc1)[C@H](C)C(O)=O
InChI
1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1
InChI key
HEFNNWSXXWATRW-JTQLQIEISA-N
基因信息
human ... IL8RA(3577) , PTGS1(5742) , PTGS2(5743)
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一般描述
( S )-(+)-布洛芬是与布洛芬抗炎操作相关的对映体,布洛芬作为一种非甾体抗炎药,以外消旋形式被广泛使用。
应用
( S )-(+)-布洛芬可用作合成水凝胶的起始物料,具有通过酶介导水解释放的潜在能力。
用于药代动力学研究的抗炎药布洛芬的对映体。
法律信息
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Journal of pharmaceutical sciences, 81(3), 221-225 (1992-03-01)
The influences of absorption rate and dosage size on the pharmacokinetics of ibuprofen (IB) enantiomers were studied in six healthy subjects. Rapidly absorbed solutions (50, 100, 200, 400, 600, and 1200 mg) and regular 600-mg tablets of racemic IB were
(S)-(+)-Ibuprofen-based hydrogelators: an approach toward anti-inflammatory drug delivery.
Tetrahedron Letters, 47(40), 7153-7156 (2006)
Enantioselective determination of ibuprofen in plasma by high-performance liquid chromatography-electrospray mass spectrometry.
Journal of Chromatography. B, Biomedical Sciences and Applications, 796(2), 413-420 (2003)
Journal of medicinal chemistry, 53(18), 6560-6571 (2010-09-02)
Following our previous research on anti-inflammatory drugs (NSAIDs), we report on the design and synthesis of 4-(aryloyl)phenyl methyl sulfones. These substances were characterized for their capacity to inhibit cyclooxygenase (COX-1 and COX-2) isoenzymes. Molecular modeling studies showed that the methylsulfone
Current medical research and opinion, 25(9), 2207-2222 (2009-07-18)
The main aim of this review was to compare the tolerability and safety between ibuprofen and paracetamol when used as anti-pyretic and analgesic agents in children up to 18 years of age. MEDLINE (1950 to November 2008), EMBASE (1980 to
Chromatograms
application for HPLCsuitable for GC我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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