一般描述
三氟甲磺酸是一种强有机酸。它可以通过双(三氟甲基硫代)水银和H2O2反应制备。它和HNO3混合,生成一种硝化试剂(一种硝基盐)。这种试剂可用于芳香化合物硝化。人们已经研究过了它在各种有机溶剂中解离状态。
应用
三氟甲磺酸可用作以下反应的催化剂:
它也可用作Fischer糖基化和Friedel-Crafts酰基化反应的催化剂。
- 在酸性条件下通过不饱和醇的环化反应制备相应的取代四氢呋喃和四氢吡喃。
- 通过醛的Schmidt反应制备相应腈。
- 通过2-烷氧羰基烯丙基硼酸酯和醛的烯丙基硼化反应制备双取代五元环内酯。
它也可用作Fischer糖基化和Friedel-Crafts酰基化反应的催化剂。
去糖基化剂
法律信息
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Danger
危险分类
Acute Tox. 4 Oral - Met. Corr. 1 - Skin Corr. 1B - STOT SE 3
靶器官
Respiratory system
WGK
WGK 1
闪点(°F)
Pensky-Martens closed cup
闪点(°C)
Pensky-Martens closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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