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Merck
CN

346640

Sigma-Aldrich

4-氟-3-硝基三氟甲苯

96%

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别名:
3-硝基-α,α,α,4-四氟甲苯, 4,α,α,α-四氟-3-硝基甲苯, FNBT
线性分子式:
FC6H3(NO2)CF3
CAS号:
分子量:
209.10
Beilstein:
1880508
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

96%

形式

liquid

折射率

n20/D 1.462 (lit.)

bp

92 °C/15 mmHg (lit.)

密度

1.494 g/mL at 25 °C (lit.)

SMILES字符串

[O-][N+](=O)c1cc(ccc1F)C(F)(F)F

InChI

1S/C7H3F4NO2/c8-5-2-1-4(7(9,10)11)3-6(5)12(13)14/h1-3H

InChI key

HLDFCCHSOZWKAA-UHFFFAOYSA-N

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应用

4-Fluoro-3-nitrobenzotrifluoride was used in the pre-column derivatization technique for HPLC with UV/VIS spectrophotometric detection of polyamines. It may be used as derivatization reagent for the HPLC determination of polyamines (spermidine, spermine and the diamine precursor putrescine). It was also used in the synthesis of:
  • 2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids
  • [3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids
  • 1-(3-chlorophenyl)-5-trifluoromethyl-3-hydrobenzimidazol-2-one

象形图

FlameExclamation mark

警示用语:

Warning

危险分类

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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Tatsuya Higashi et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 18(12), 1301-1307 (2002-12-28)
Derivatization of neutral steroids for increasing sensitivity in liquid chromatography/negative atmospheric pressure chemical ionization-mass spectrometry (APCI-MS) has been examined. Under APCI conditions, gas-phase electrons are provided by the corona discharge and captured by electron-affinitive compounds. In negative APCI-MS, therefore, ultrahigh
B.P. Spragg, A.D. Hutchings
Journal of Chromatography A, 258, 289-289 (1983)
C Molins-Legua et al.
The Analyst, 124(4), 477-482 (1999-12-22)
The derivatization of biogenic amines such as putrescine, cadaverine, spermidine and spermine with dansyl chloride in solid phase extraction cartridges is described. Different types of filling materials were tested in order to have the highest retention of the different analytes.
Emanuela Caci et al.
American journal of physiology. Lung cellular and molecular physiology, 285(1), L180-L188 (2003-03-26)
Activators of the CFTR Cl- channel may be useful for therapy of cystic fibrosis. Short-circuit current (Isc) measurements were done on human bronchial epithelial cells to characterize the best flavone and benzimidazolone CFTR activators identified by lead-based combinatorial synthesis and

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