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质量水平
检测方案
99%
形式
liquid
折射率
n20/D 1.305 (lit.)
bp
142 °C (lit.)
密度
1.93 g/mL at 25 °C (lit.)
SMILES字符串
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br
InChI
1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26
InChI key
WTWWXOGTJWMJHI-UHFFFAOYSA-N
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一般描述
1-溴十七氟辛烷(全氟辛基溴)是一种全氟化碳。使用精氨酸-甘氨酸-天冬氨酸 (RGD) 多肽对全氟辛基溴的聚乙二醇化聚酯纳米胶囊进行表面修饰,用于肿瘤成像。全氟辛基溴纳米胶囊已被开发作为超声和磁共振成像 (MRI) 的双重造影剂。
应用
1-溴十七氟辛烷(全氟辛基溴)可作为氟-19 磁共振成像血管系统造影剂或用于合成氧载体。它也被用作血液替代品乳剂中的氧载体。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Journal of pharmaceutical and biomedical analysis, 51(4), 894-900 (2009-11-10)
The aim of this study was to assess the herceptin efficacy in ex vivo cultures of MCF-7 breast carcinoma cells. Herceptin was used with perfluorooctyl bromide (PFOB) and conjugated with lipoplex, containing plasmid DNA and lipofectamine (LipA), to allow fluorine-19
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 31(10), 1718-1720 (2011-10-27)
To investigate the effect of temperature on the partition coefficient of isoflurane and sevoflurane in perflurocarbonate emulsion (Oxygent(TM)). The partition coefficients of isoflurane and sevoflurane in perflurocarbonate emulsion (Oxygent(TM)) were measured at different temperatures (4, 22, 27, 32 and 37
Journal of magnetic resonance imaging : JMRI, 2(1), 53-61 (1992-01-01)
Perfluorocarbons such as perfluoroctylbromide (PFOB) can be used as contrast agents in the vascular system for fluorine-19 magnetic resonance imaging or as synthetic oxygen carriers. F-19 imaging has been proposed for studying the vascular system, capillary flow, tissue perfusion, and
Anesthesia and analgesia, 110(6), 1661-1668 (2010-05-08)
Functional magnetic resonance imaging (fMRI) of fluorine-19 allows for the mapping of oxygen partial pressure within perfluorocarbons in the alveolar space (Pao(2)). Theoretically, fMRI-detected Pao(2) can be combined with the Fick principle approach, i.e., a mass balance of oxygen uptake
Nanocapsules of perfluorooctyl bromide for theranostics: from formulation to in vivo targeting.
SPIE Proc., 8955 (2014)
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