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Merck
CN

318426

碘化3,3′-二己基氧羰花青

98%

别名:

3-己基-2-[3-(3-己基-2 (3 H ) 苯并恶唑亚甲基)-1-丙烯基] 苯并恶唑碘化物

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关于此项目

经验公式(希尔记法):
C29H37IN2O2
化学文摘社编号:
分子量:
572.52
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
9312562
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产品名称

碘化3,3′-二己基氧羰花青, 98%

InChI

1S/C29H37N2O2.HI/c1-3-5-7-13-22-30-24-16-9-11-18-26(24)32-28(30)20-15-21-29-31(23-14-8-6-4-2)25-17-10-12-19-27(25)33-29;/h9-12,15-21H,3-8,13-14,22-23H2,1-2H3;1H/q+1;/p-1

SMILES string

[I-].CCCCCCN1\C(Oc2ccccc12)=C\C=C\c3oc4ccccc4[n+]3CCCCCC

InChI key

XVLXYDXJEKLXHN-UHFFFAOYSA-M

assay

98%

form

powder or chunks

technique(s)

titration: suitable

mp

219-221 °C (lit.)

solubility

chloroform: 25 mg/mL, clear to slightly hazy, orange

λmax

485 nm

ε (extinction coefficient)

≥120000 at 483-488 nm in methanol at 0.01 g/L

fluorescence

λex 485 nm; λem 501 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

碘代3,3′-二己氧杂羰花青已用于:
  • 植物根和苔类内生子囊菌的选择性染色
  • 可视化血栓生成和血小板聚集
  • 可视化氯吡脲(FCF)诱导的线粒体形态变化

General description

碘代3,3′-二己氧杂羰花青(DiOC6)是用于离体活体染色的亲脂性荧光色素。这种阳离子型染料可用于动物和植物细胞的线粒体和内质网染色。还可用于植物根和苔类内生子囊菌的快速、一致和高度选择性的荧光染色。DiOC6还可用于检测细胞凋亡早期发生的不同线粒体变化。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ashlesha A Kadam et al.
Biochimica et biophysica acta, 1861(1 Pt A), 2942-2955 (2016-10-23)
Apoptosis Inducing Factor (AIF), a phylogenetically conserved mitochondrial inter-membrane space flavoprotein has an important role in caspase independent cell death. Nevertheless, AIF is also essential for cell survival. It is required for mitochondrial organization and energy metabolism. Upon apoptotic stimulation
Yanyan Zheng et al.
European journal of medicinal chemistry, 125, 902-913 (2016-10-22)
Emodin, a natural anthraquinone derivative isolated from Rheum palmatum L., has been demonstrated to exhibit good anti-cancer effect. In this study, a series of novel quaternary ammonium salts of emodin, anthraquinone and anthrone were synthesized and their anticancer activities were
Comparison of DiOC6 (3) uptake and annexin V labeling for quantification of apoptosis in leukemia cells and non-malignant T lymphocytes from children
Ozgen u, et al.
Cytometry, 42(1), 74-78 (2000)
Xueying Zhuang et al.
Mycological research, 113(Pt 4), 417-431 (2008-12-31)
Growth and organelle morphology in the wood rotting basidiomycete fungus Phanerochaete velutina were examined in Petri dishes, on agar-coated slides, and in submerged cultures, using DIC, fluorescence and four-dimensional (4-D; x,y,z,t) confocal microscopy, with several fluorescent probes. Phanerochaete is ideal
Microfluidic cell sorting: Towards improved biocompatibility of extracorporeal lung assist devices
Bleilevens C, et al.
Scientific reports, 8(1), 8031-8031 (2018)

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