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Merck
CN
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文件

318426

Sigma-Aldrich

碘化3,3′-二己基氧羰花青

98%

别名:

3-己基-2-[3-（3-己基-2 (3 H ) 苯并恶唑亚甲基）-1-丙烯基] 苯并恶唑碘化物

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About This Item

经验公式（希尔记法）:
C29H37IN2O2
CAS号:
53213-82-4
分子量:
572.52
Beilstein:
9312562
MDL编号:
MFCD00011954
UNSPSC代码:
12171500
PubChem化学物质编号:
24859130
NACRES:
NA.47

质量水平

100

检测方案

98%

形式

powder or chunks

mp

219-221 °C (lit.)

溶解性

chloroform: 25 mg/mL, clear to slightly hazy, orange

λmax

485 nm

ε (消光系数)

≥120000 at 483-488 nm in methanol at 0.01 g/L

荧光

λex 485 nm; λem 501 nm in methanol

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

[I-].CCCCCCN1\C(Oc2ccccc12)=C\C=C\c3oc4ccccc4[n+]3CCCCCC

InChI

1S/C29H37N2O2.HI/c1-3-5-7-13-22-30-24-16-9-11-18-26(24)32-28(30)20-15-21-29-31(23-14-8-6-4-2)25-17-10-12-19-27(25)33-29;/h9-12,15-21H,3-8,13-14,22-23H2,1-2H3;1H/q+1;/p-1

InChI key

XVLXYDXJEKLXHN-UHFFFAOYSA-M

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相关类别

一般描述

碘代3,3′-二己氧杂羰花青(DiOC6)是用于离体活体染色的亲脂性荧光色素。这种阳离子型染料可用于动物和植物细胞的线粒体和内质网染色。还可用于植物根和苔类内生子囊菌的快速、一致和高度选择性的荧光染色。DiOC6还可用于检测细胞凋亡早期发生的不同线粒体变化。

应用

碘代3,3′-二己氧杂羰花青已用于：
  • 植物根和苔类内生子囊菌的选择性染色
  • 可视化血栓生成和血小板聚集
  • 可视化氯吡脲(FCF)诱导的线粒体形态变化

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Ashlesha A Kadam et al.
Biochimica et biophysica acta, 1861(1 Pt A), 2942-2955 (2016-10-23)
Apoptosis Inducing Factor (AIF), a phylogenetically conserved mitochondrial inter-membrane space flavoprotein has an important role in caspase independent cell death. Nevertheless, AIF is also essential for cell survival. It is required for mitochondrial organization and energy metabolism. Upon apoptotic stimulation
Yanyan Zheng et al.
European journal of medicinal chemistry, 125, 902-913 (2016-10-22)
Emodin, a natural anthraquinone derivative isolated from Rheum palmatum L., has been demonstrated to exhibit good anti-cancer effect. In this study, a series of novel quaternary ammonium salts of emodin, anthraquinone and anthrone were synthesized and their anticancer activities were
Xueying Zhuang et al.
Mycological research, 113(Pt 4), 417-431 (2008-12-31)
Growth and organelle morphology in the wood rotting basidiomycete fungus Phanerochaete velutina were examined in Petri dishes, on agar-coated slides, and in submerged cultures, using DIC, fluorescence and four-dimensional (4-D; x,y,z,t) confocal microscopy, with several fluorescent probes. Phanerochaete is ideal
Comparison of DiOC6 (3) uptake and annexin V labeling for quantification of apoptosis in leukemia cells and non-malignant T lymphocytes from children
Ozgen u, et al.
Cytometry, 42(1), 74-78 (2000)
Examination of living and fixed gametes and early embryos stained with supravital fluorochromes (Hoechst 33342 and 3, 3?-dihexyloxacarbocyanine iodide)
Luttmer SJ and Longo FJ
Gamete Research, 15(3), 267-283 (1986)
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