301930
2,2-二(溴甲基)-1,3-丙二醇
98%
别名:
1,3-二溴-2,2-双（羟甲基）丙烷, 二溴新戊二醇, 戊四醇二溴化物, 戊四醇二溴水合物
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关于此项目
线性分子式:
HOCH2C(CH2Br)2CH2OH
化学文摘社编号:
分子量:
261.94
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
221-967-7
MDL number:
InChI key
CHUGKEQJSLOLHL-UHFFFAOYSA-N
InChI
1S/C5H10Br2O2/c6-1-5(2-7,3-8)4-9/h8-9H,1-4H2
SMILES string
OCC(CO)(CBr)CBr
vapor pressure
10 mmHg ( 178 °C)
assay
98%
form
solid
mp
112-114 °C (lit.)
Quality Level
signalword
Danger
hcodes
Hazard Classifications
Carc. 1B - Muta. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
K A Treinen et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 13(2), 245-255 (1989-08-01)
The effect of 2,2-bis(bromomethyl)-1,3-propanediol (BMP) on reproduction in Swiss CD-1 mice was evaluated by use of a continuous breeding protocol. BMP was administered in the feed at 0.1, 0.2, and 0.4% concentrations. Both male and female F0 mice (20 pairs
J Sun
Biometrics, 55(4), 1273-1276 (2001-04-21)
Historical control data are often available in carcinogenicity studies and are included for testing dose effects in current studies. A new method is developed for incorporating the historical control information into a dose effect test. The method generalizes the test
Weixi Kong et al.
Toxicology letters, 222(3), 273-279 (2013-08-21)
2,2-Bis(bromomethyl)-1,3-propanediol (BMP) is a brominated flame retardant used in urethane foams and polyester resins. In a two year dietary study, BMP caused neoplastic lesions at multiple sites including the urinary bladder of both rats and mice. However, liver was not
Shai Ezra et al.
Journal of contaminant hydrology, 86(3-4), 195-214 (2006-05-13)
This study investigates the mechanisms controlling the distribution of 3-bromo-2,2-bis(bromomethyl)propanol (TBNPA) and 2,2-bis(bromomethyl)propan-1,3-diol (DBNPG) in a fractured chalk aquitard. An extensive monitoring program showed a systematic decrease in the TBNPA/DBNPG ratio with distance from the contamination source. Sorption of TBNPA
Simone I Hoehle et al.
Drug metabolism and disposition: the biological fate of chemicals, 37(2), 408-416 (2008-11-26)
2,2-Bis(bromomethyl)-1,3-propanediol (BMP) is a brominated flame retardant, previously shown to be a multisite carcinogen in experimental animals. Studies were performed to characterize the dispositional and metabolic fate of BMP after oral or intravenous administration to male Fischer-344 rats. After a
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