所有图片(1)
别名:
Bromomethylmagnesium
线性分子式:
CH3MgBr
CAS号:
分子量:
119.24
Beilstein:
3535220
MDL编号:
UNSPSC代码:
12352111
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
反应适用性
reaction type: Grignard Reaction
浓度
1.4 M in THF: toluene (1:3)
密度
1.018 g/mL at 25 °C
SMILES字符串
C[Mg]Br
InChI
1S/CH3.BrH.Mg/h1H3;1H;/q;;+1/p-1
InChI key
AVFUHBJCUUTGCD-UHFFFAOYSA-M
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应用
Methylmagnesium bromide is generally used as a Grignard reagent for C-C bond formation by reacting with the carbonyl groups of aldehydes and ketones.
警示用语：
Danger
危险分类
Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT RE 2 - STOT SE 3 - Water-react 1
靶器官
Central nervous system, Respiratory system
补充剂危害
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
监管及禁止进口产品
Alcohols: Reactions and Synthesis
Organic Chemistry Study Guide: Key Concepts, Problems, and Solutions (2015)
Snahel Patel et al.
Journal of medicinal chemistry, 58(1), 401-418 (2014-10-24)
Dual leucine zipper kinase (DLK, MAP3K12) was recently identified as an essential regulator of neuronal degeneration in multiple contexts. Here we describe the generation of potent and selective DLK inhibitors starting from a high-throughput screening hit. Using proposed hinge-binding interactions
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