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Merck
CN

258385

Sigma-Aldrich

原卟啉 IX 二钠盐

≥90% (HPLC)

别名:

3,7,12,17-四甲基-8,13-二乙烯基-2,18-卟吩二丙酸 二钠盐, 原卟啉钠, 蛋壳卟啉 二钠盐

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About This Item

经验公式(希尔记法):
C34H32N4Na2O4
CAS号:
分子量:
606.62
Beilstein:
5227034
EC 号:
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.23

质量水平

检测方案

≥90% (HPLC)

形式

powder

λmax

406 nm

储存温度

2-8°C

SMILES字符串

[Na+].[Na+].Cc1c(CCC([O-])=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C=C)c5C)c(C=C)c4C)c(C)c3CCC([O-])=O

InChI

1S/C34H34N4O4.2Na/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16,36-37H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);;/q;2*+1/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChI key

JZRNDUPVNXWZDY-HXFTUNQESA-L

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应用

原始卟啉二钠盐(PpIX)用作研究中荧光光谱表征的染料含量。在一项研究中报道了PpIX对肉瘤180实体瘤细胞的细胞毒性作用。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Filipa L Sousa et al.
Genome biology and evolution, 5(1), 200-216 (2012-12-22)
An open question regarding the evolution of photosynthesis is how cyanobacteria came to possess the two reaction center (RC) types, Type I reaction center (RCI) and Type II reaction center (RCII). The two main competing theories in the foreground of
Pan Wang et al.
Ultrasonics, 53(5), 935-942 (2013-02-19)
Protoporphyrin IX (PpIX) has been used as a sensitizer in photodynamic therapy (PDT) as well as in sonodynamic therapy (SDT). The photo-bleaching of PpIX has been well investigated in many experimental systems and some photo-products have also been identified in
Hirotsugu Kobuchi et al.
PloS one, 7(11), e50082-e50082 (2012-11-29)
Accumulation of protoporphyrin IX (PpIX) in malignant cells is the basis of 5-aminolevulinic acid (ALA)-mediated photodynamic therapy. We studied the expression of proteins that possibly affect ALA-mediated PpIX accumulation, namely oligopeptide transporter-1 and -2, ferrochelatase and ATP-binding cassette transporter G2
Agata Nowak-Stępniowska et al.
Acta biochimica Polonica, 59(4), 603-611 (2012-11-29)
Mitochondria are cell energetic centers where ATP is produced. They also play a very important role in the PDT as intracellular sites of photosensitizer localization. Photosensitizers gathering in mitochondria (like porphyrin derivatives used in this work) are more effective in
Kana Unuma et al.
PloS one, 8(2), e56526-e56526 (2013-03-05)
Lipopolysaccharide (LPS)-induced myocardial dysfunction is caused, at least in part, by mitochondrial dysfunction. Mitochondrial dysfunction and the oxidative damage associated with it are scavenged through various cellular defense systems such as autophagy to prevent harmful effects. Our recent study has

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