254916
7,8-二羟基-6-甲氧基香豆素
98%
别名:
秦皮素
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关于此项目
经验公式（希尔记法）:
C10H8O5
化学文摘社编号:
分子量:
208.17
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
209-376-2
MDL number:
InChI key
HAVWRBANWNTOJX-UHFFFAOYSA-N
InChI
1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
SMILES string
COc1cc2C=CC(=O)Oc2c(O)c1O
assay
98%
form
powder
mp
230-231 °C (lit.)
Quality Level
General description
7,8-Dihydroxy-6-methoxycoumarin is a versatile compound known for its unique fluorescence properties and its role as a photoinitiator in polymerization processes. It exhibits high reactivity under UV light, making it an ideal candidate for applications in the polymerization industry, particularly in the formulation of coatings, adhesives, and inks. It is also used in biomedical applications, such as drug delivery due to its biocompatibility.
Application
7,8-Dihydroxy-6-methoxycoumarincan be used as a UV absorber in polymer formulations. Its ability to absorbultraviolet light helps in protecting polymers from degradation caused by UVradiation, thereby improving their longevity and stability.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
M Francisca Molina-Jimenez et al.
European journal of pharmacology, 472(1-2), 81-87 (2003-07-16)
The purpose of this study was to investigate the potential neuroprotective effects of myricetin (flavonoid) and fraxetin (coumarin) on rotenone-induced apoptosis in SH-SY5Y cells, and the possible signal pathway involved in a neuronal cell model of Parkinson's disease. These two
B Fernandez-Puntero et al.
Biological & pharmaceutical bulletin, 24(7), 777-784 (2001-07-18)
The aim of this paper was to study the influence of Fraxetin (7,8-dihydroxy-6-methoxv coumarin) treatment in a Drosophila melanogaster experimental model, analyzing several parameters in normal situations and instances of induced oxidative stress. Fraxetin treatment was introduced at different ages.
Phuong Thien Thuong et al.
Biological & pharmaceutical bulletin, 32(9), 1527-1532 (2009-09-02)
Atherosclerosis is main cause of arteriosclerosis. The pivotal role of low-density lipoprotein (LDL) oxidation in atherogenesis suggests antioxidants may help prevent cardiovascular disease. Fraxinus rhynchophylla DENCE (Oleaceae) is a traditional medicinal plant from East Asia. During the course of characterizing
S Martín-Aragón et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 52(1-2), 55-59 (1997-01-01)
We have evaluated the effects of an oral treatment of mice with fraxetin (25 mg/kg for 30 days) on the glutathione system (GSH, GSSG, and GSSG/GSH ratio as stress index), glutathione reductase (GR) and glutathione peroxidase (GPx) in liver supernatants
Po-Lin Kuo et al.
International immunopharmacology, 6(7), 1167-1175 (2006-05-23)
The survival of osteoblast cells is one of the determinants of the development of osteoporosis in patients with inflamed synovium, such as in rheumatoid arthritis (RA). By means of alkaline phosphatase (ALP) activity and osteocalcin ELISA assay, we have shown
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