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Merck
CN

202533

二环氧化-1,3-丁二烯

97%

别名:

1,2,3,4-二环氧丁烷

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关于此项目

经验公式(希尔记法):
C4H6O2
化学文摘社编号:
分子量:
86.09
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8614599
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InChI

1S/C4H6O2/c1-3(5-1)4-2-6-4/h3-4H,1-2H2

SMILES string

C1OC1C2CO2

InChI key

ZFIVKAOQEXOYFY-UHFFFAOYSA-N

vapor pressure

25 mmHg ( 56 °C)

assay

97%

form

liquid

impurities

<3% methylene chloride

refractive index

n20/D 1.434 (lit.)

bp

56-58 °C/25 mmHg (lit.)

mp

2-4 °C (lit.)

density

1.113 g/mL at 25 °C (lit.)

storage temp.

2-8°C

Quality Level

General description

1,3-二环氧丁烷是多功能有机化合物,具有二个环氧基组成的双环氧化物结构。这一特性令其在聚合反应中发挥有效的交联作用,提高产物的机械强度和热稳定性。

Application

1,3-二环氧丁烷可用于:
  • 作为前体合成用于药物递送和组织工程的聚氨基醇醚微结构水凝胶。有助于提高水凝胶的机械强度和热响应能力。
  • 作为胶体通过绿色合成法制备环氧-胺止血海绵用于控制出血。它可促进环氧-胺基质中的三维网络形成。

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 1B - Skin Corr. 1B

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

114.8 °F - closed cup

flash_point_c

46 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

非剧毒-急性毒性1
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Michelle L Webb et al.
The Journal of hand surgery, 36(6), 1052-1057 (2011-04-26)
Fanconi anemia (FA) is a rare genetic disorder of DNA repair that with near uniformity leads to bone marrow failure and resulting morbidity and mortality. Approximately 50% of FA patients are born with anomalies of the thumb or thumb and
Melissa Goggin et al.
Chemical research in toxicology, 24(6), 809-817 (2011-04-02)
1,3-Butadiene (BD) is an important industrial and environmental chemical classified as a human carcinogen. The mechanism of BD-mediated cancer is of significant interest because of the widespread exposure of humans to BD from cigarette smoke and urban air. BD is
Melissa Goggin et al.
Chemical research in toxicology, 23(4), 808-812 (2010-03-17)
1,3-Butadiene (BD) is an important industrial and environmental chemical classified as a human carcinogen on the basis of epidemiological evidence for an increased incidence of leukemia in workers occupationally exposed to BD and its carcinogenicity in laboratory rats and mice.
Emily C Minerath et al.
Environmental science & technology, 43(21), 8133-8139 (2009-11-21)
Polyols and organic sulfates have recently been identified in the secondary organic aerosol (SOA) formed in the photooxidation of isoprene in both the laboratory and under ambient atmospheric conditions. Nuclear magnetic resonance methods were used to monitor the bulk reaction
Ying Wen et al.
Mutation research, 716(1-2), 84-91 (2011-09-07)
1,3-Butadiene (BD) is an air pollutant and a known carcinogen. 1,2,3,4-Diepoxybutane (DEB), one of the major in vivo metabolites of BD, is considered the ultimate culprit of BD mutagenicity/carcinogenicity. DEB is a bifunctional alkylating agent, being capable of inducing the

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