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Merck
CN

194905

Sigma-Aldrich

12-冠醚-4

98%

别名:

1,4,7,10-四氧环十二烷

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About This Item

经验公式(希尔记法):
C8H16O4
CAS号:
分子量:
176.21
Beilstein:
1363064
EC 号:
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

表单

liquid

折射率

n20/D 1.463 (lit.)

沸点

61-70 °C/0.5 mmHg (lit.)

mp

16 °C (lit.)

密度

1.089 g/mL at 25 °C (lit.)

官能团

ether

SMILES字符串

C1COCCOCCOCCO1

InChI

1S/C8H16O4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h1-8H2

InChI key

XQQZRZQVBFHBHL-UHFFFAOYSA-N

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一般描述

12-冠醚-4是一种冠醚,通常用作配位化学中的配体。由于对锂阳离子具有很强的特异性螯合能力,它还是一种锂离子载体。

应用

12-冠醚-4可用作:
  • 通过阴离子开环聚合反应以六乙基环三硅氧烷单体和NaOH催化剂合成聚(二乙基硅氧烷) (PDES)
  • 作为添加剂用于通过芳基溴与二芳基甲烷之间的钯催化交叉偶联反应制备三芳基甲烷衍生物
  • 有机合成中的相转移催化剂

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 1 Inhalation

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Preparation of poly (diethylsiloxane) with the NaOH/12-crown-4 catalyst
Hedden RC and Cohen C
Polymer, 41(18), 6975-6979 (2000)
Zehra Edis et al.
Pathogens (Basel, Switzerland), 8(4) (2019-10-30)
Antimicrobial agents containing symmetrical triiodides complexes with halogen bonding may release free iodine molecules in a controlled manner. This happens due to interactions with the plasma membrane of microorganisms which lead to changes in the structure of the triiodide anion.
Mazhar Ali Abbasi et al.
Sensors (Basel, Switzerland), 12(11), 15424-15437 (2012-12-04)
In this study honeycomb-like NiO nanostructures were grown on nickel foam by a simple hydrothermal growth method. The NiO nanostructures were characterized by field emission electron microscopy (FESEM), high resolution transmission electron microscopy (HRTEM) and X-ray diffraction (XRD) techniques. The
Márkó Grabarics et al.
The Analyst, 145(19), 6313-6333 (2020-07-28)
In the past decade, ion mobility spectrometry (IMS) in combination with mass spectrometry (IM-MS) became a widely employed technique for the separation and structural characterization of ionic species in the gas phase. Similarly to chromatography, where studies on the mechanism
Multilayered ion-imprinted membranes with high selectivity towards Li+ based on the synergistic effect of 12-crown-4 and polyether sulfone
Lu J, et al.
Applied Surface Science, 427, 931-941 (2018)

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