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Merck
CN

189901

Sigma-Aldrich

甲基氯化镁 溶液

3.0 M in THF

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别名:
Chloromethylmagnesium, Methyl magnesium chloride, Methylmagnesiumchloride
线性分子式:
CH3MgCl
CAS号:
分子量:
74.79
Beilstein:
3587199
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.22

自燃温度

609 °F

质量水平

反应适用性

reaction type: Grignard Reaction

浓度

3.0 M in THF

密度

1.013 g/mL at 25 °C

SMILES字符串

C[Mg]Cl

InChI

1S/CH3.ClH.Mg/h1H3;1H;/q;;+1/p-1

InChI key

RQNMYNYHBQQZSP-UHFFFAOYSA-M

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应用

将甲基氯化镁溶液(3M,溶于THF中)用二醛糖衍生的硝酮进行1,3-加成反应,可形成 N-苄基羟胺。通过这些N-苄基羟胺的N-O键的还原裂解,可产生N-苄氨基糖,其是生物活性化合物的关键基团。它还可以与Garner型醛反应形成相应的仲醇。

包装

建议将25 mL Sure/Seal 瓶作为一次性瓶使用。 反复穿刺可能会导致产品性能下降。

法律信息

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

警示用语:

Danger

危险分类

Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1

靶器官

Central nervous system, Respiratory system

补充剂危害

WGK

WGK 1

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

危险化学品

分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Is the BHT inhibitor present in Product 189901, Methylmagnesium chloride solution?

    Yes, BHT is present in the THF. This information can be found on the MSDS, which is available from our website.

  6. Can Product 189901, Methylmagnesium chloride solution, be used if a precipitate is present?

    If a precipitate is present, the product can be heated and stirred until the precipitate is dissolved.

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

A new route to aminosugars from sugar nitrones: synthesis of 6-deoxynojirimycin.
Dhavale DD
Tetrahedron Asymmetry, 8(9), 1475-1486 (1997)

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