质量水平
检测方案
99%
形式
liquid
包含
sodium fluoride as stabilizer
折射率
n20/D 1.373 (lit.)
bp
54-55 °C/34 mmHg (lit.)
密度
1.24 g/mL at 25 °C (lit.)
SMILES字符串
OC(CF)CF
InChI
1S/C3H6F2O/c4-1-3(6)2-5/h3,6H,1-2H2
InChI key
PVDLUGWWIOGCNH-UHFFFAOYSA-N
应用
1,3-Difluoro-2-propanol was used in the synthesis of 1,3-difluoroacetone.
警示用语：
Warning
危险分类
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
107.6 °F
闪点(°C)
42 °C
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
M G Feldwick et al.
Journal of biochemical and molecular toxicology, 12(1), 41-52 (1998-01-01)
Administration to rats of 1,3-difluoro-2-propanol (100 mg kg-1 body weight), the major ingredient of the pesticide gliftor, resulted in accumulation of citrate in the kidney after a 3 hour lag phase. 1,3-Difluoro-2-propanol was found to be metabolized to 1,3-difluoroacetone and
K I Menon et al.
Journal of biochemical and molecular toxicology, 15(1), 47-54 (2001-02-15)
The biochemical toxicology of 1,3-difluoroacetone, a known metabolite of the major ingredient of the pesticide Gliftor (1,3-difluoro-2-propanol), was investigated in vivo and in vitro. Rat kidney homogenates supplemented with coenzyme A, ATP, oxaloacetate, and Mg2+ converted 1,3-difluoroacetone to (-)-erythro-fluorocitrate in
M J Garle et al.
Xenobiotica; the fate of foreign compounds in biological systems, 29(5), 533-545 (1999-06-24)
1. This study has examined the ability of dichloropropanols, haloalcohols and their putative metabolites to deplete glutathione when incubated with liver fractions obtained from untreated and differentially induced rats. 2. 1,3-Dichloropropan-2-ol and 2,3-dichloropropan-1-ol (0-1000 microM) both depleted glutathione in a
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