跳转至内容
Merck
CN
所有图片(5)

文件

130672

Sigma-Aldrich

N-羟基丁二酰亚胺

98%

登录查看公司和协议定价
所有图片(5)
别名:
1-羟基-2,5-吡咯烷二酮, HOSu, NHS
经验公式（希尔记法）:
C4H5NO3
CAS号:
6066-82-6
分子量:
115.09
Beilstein:
113913
EC 号:
228-001-3
MDL编号:
MFCD00005516
UNSPSC代码:
12352115
PubChem化学物质编号:
24847975
NACRES:
NA.22

质量水平

200

检测方案

98%

形式

solid

mp

95-98 °C (lit.)

SMILES字符串

ON1C(=O)CCC1=O

InChI

1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2

InChI key

NQTADLQHYWFPDB-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

应用

N-羟基琥珀酰亚胺可以在存在二环己基碳二亚胺的条件下在羧酸中通过脱水反应合成N-羟基琥珀酰亚胺酯。
N-羟基琥珀酰亚胺已用于中间介质的合成如：
  • N

  • -丁二酰亚胺3-(二-三-丁基氟硅烷）苯甲酸
  • 4-[2,2-双[(对-甲苯磺酰)-甲基]乙酰]苯甲酸-NHS酯
  • N-丁二酰亚胺3-碘苯甲酸

它还用于微流体整合的表面等离子体共振（SPR）平台的微通道的表面修饰的实验方法中，用于对细菌病原体进行检测和定量。
碳二亚胺方法中使用的添加剂用于改良的酰胺化及肽偶联。

象形图

Corrosion
GHS05

警示用语：

Danger

危险声明

H315,H318

危险分类

Eye Dam. 1 - Skin Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the solution stability of Product 130672, N-Hydroxysuccinimide?

    Sigma-Aldrich does not evaluate 130672 for solution stability. Therefore, it is advisable to prepare a solution fresh for each use. Please note, the product is moisture sensitive.

  6. What is the purity of Product 130672, N-Hydroxysuccinimide?

    The purity is lot specific and will be stated on the Specification Sheet.

  7. Does N-Hydroxysuccinimide go by any other names?

    Yes, N-Hydroxysuccinimide is also referred to by the acronym NHS and is also referred to by the synonyms 1-Hydroxy-2,5-pyrrolidinedione and HOSu.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Polycyclic Aromat. Compd., 3, 781-781 (1993)
Zbigniew Czajgucki et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(10), 653-662 (2006-07-19)
Edeines are pentapeptide amide antibiotics composed of four nonprotein amino acids, glycine, and polyamine. They exhibit antimicrobial and immunosuppressive activities and are universal inhibitors of translation. Moreover, it was proven that the free ionizable carboxy group in the (2R, 6S
PEGylation of native disulfide bonds in proteins.
Brocchini S
Nature Protocols, 1(5), 2241-2241 (2006)
Cong Li et al.
Journal of the American Chemical Society, 128(47), 15072-15073 (2006-11-23)
The conjugate of bacterial cytosine deaminase (bCD) and poly-l-lysine (PLL) that was functionalized with biotin, rhodamine, and Gd3+-DOTA was synthesized and characterized. It demonstrated high relaxivity, improved enzymatic specificity to prodrug 5-fluorocytosine, low cytotoxicity, efficient cell uptake, and high enzymatic
D Sehgal et al.
Analytical biochemistry, 218(1), 87-91 (1994-04-01)
Water-soluble carbodiimides are widely used for carboxyl-amine conjugation. However, extremely variable and low yields, obtained under a variety of conditions, have been a serious problem in the coupling. A simple method, optimizing various parameters of the coupling reaction, in which
查看所有相关文献

商品

Molecular Monolayers on Silicon Surfaces

Explore methods for molecular monolayers on silicon surfaces, their properties, and applications in molecular electronics and sensing.

Functionalized Graphene Oxide: Properties & Applications

Professor Aran discusses engineering graphene-based materials through careful functionalization, enabling diverse applications.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门