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Merck
CN

126896

Sigma-Aldrich

间氟苄胺

97%

别名:

(3-Fluorophenyl)methanamine, 1-(3-Fluorophenyl)methanamine, 3-Fluorobenzenemethanamine, 3-Fluorophenylmethylamine, m-Fluorobenzylamine

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About This Item

线性分子式:
FC6H4CH2NH2
CAS号:
分子量:
125.14
EC 号:
MDL编号:
UNSPSC代码:
12352100
eCl@ss:
39040408
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

97%

表单

liquid

折射率

n20/D 1.514 (lit.)

密度

1.097 g/mL at 25 °C (lit.)

官能团

amine
fluoro

SMILES字符串

NCc1cccc(F)c1

InChI

1S/C7H8FN/c8-7-3-1-2-6(4-7)5-9/h1-4H,5,9H2

InChI key

QVSVMNXRLWSNGS-UHFFFAOYSA-N

应用

3-Fluorobenzylamine has been used to study the rate of reaction of benzylamines with 1-Chloro-2,4-dinitrobenzene and toluene-p-sulphonyl chloride. It has also been used in the synthesis of substituted amino-sulfonamide protease inhibitors (PIs) DPC 681 and DPC 684.

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

159.8 °F - closed cup

闪点(°C)

71 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Fischer A, et al.
Journal of the Chemical Society B: Physical Organic, 466-468 (1966)
A Paden King et al.
Dalton transactions (Cambridge, England : 2003), 48(18), 5987-6002 (2019-01-24)
Four cobalt(iii) complexes of the general formula [Co(Schiff base)(L)2]+, where L is ammonia (NH3) or 3-fluorobenzylamine (3F-BnNH2), were synthesized. The complexes were characterized by NMR spectroscopy, mass spectrometry, and X-ray crystallography. Their electrochemical properties, ligand substitution mechanisms, and ligand exchange
R F Kaltenbach et al.
Antimicrobial agents and chemotherapy, 45(11), 3021-3028 (2001-10-16)
Human immunodeficiency virus (HIV) protease inhibitors (PIs) are important components of many highly active antiretroviral therapy regimens. However, development of phenotypic and/or genotypic resistance can occur, including cross-resistance to other PIs. Development of resistance takes place because trough levels of
Hua-Li Yang et al.
European journal of medicinal chemistry, 138, 715-728 (2017-07-21)
A series of coumarin-pargyline hybrids (4a-x) have been designed, synthesized and evaluated as novel dual inhibitors of Alzheimer's disease (AD). Most of the compounds exhibited a potent ability to inhibit amyloid-β (Aβ) aggregation and monoamine oxidases. In particular, compound 4x
Simon H Rüdisser et al.
Journal of biomolecular NMR, 74(10-11), 579-594 (2020-06-20)
Fluorine NMR has recently gained high popularity in drug discovery as it allows efficient and sensitive screening of large numbers of ligands. However, the positive hits found in screening must subsequently be ranked according to their affinity in order to

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