124192
1,4-丁二醇二缩水甘油醚
technical grade, 60%
别名:
1,4-丁二醇二缩水甘油醚, 1,4-双（2,3-环氧丙氧基）丁烷, 1,4-双（环氧乙烷-2-基甲氧基）丁烷, 1,4-双（缩水甘油基氧基） 丁烷, 四亚甲基二醇二缩水甘油醚
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关于此项目
经验公式（希尔记法）:
C10H18O4
化学文摘社编号:
分子量:
202.25
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
219-371-7
Beilstein/REAXYS Number:
115238
MDL number:
产品名称
1,4-丁二醇二缩水甘油醚, technical grade, 60%
InChI key
SHKUUQIDMUMQQK-UHFFFAOYSA-N
InChI
1S/C10H18O4/c1(3-11-5-9-7-13-9)2-4-12-6-10-8-14-10/h9-10H,1-8H2
SMILES string
C(CCOCC1CO1)COCC2CO2
grade
technical grade
vapor pressure
~10 mmHg ( 20 °C)
form
liquid
concentration
60%
refractive index
n20/D 1.453 (lit.)
bp
266 °C (lit.)
density
1.1 g/mL at 25 °C (lit.)
Quality Level
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Application
1,4-丁二醇二缩水甘油醚可用于：
- 作为交联剂制备透明质酸皮肤填充剂。这种交联过程增强了填充剂的凝胶状一致性，使其更耐用且更持久。
- 作为单体，制备基于环氧树脂的石墨烯纳米复合材料，这些材料在柔性电子、防腐涂层和导电胶黏剂领域具有潜在应用。BDDE因其低粘度、良好的反应性和与石墨烯的相容性等理想特性而被选用。
General description
1,4-丁二醇二缩水甘油醚（BDDE）是带两个环氧基团的同双官能团单体，广泛用于改性环氧树脂的粘度。它也用作合成聚合物网络的交联剂。
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Comparative physicochemical analysis among 1, 4-butanediol diglycidyl ether cross-linked hyaluronic acid dermal fillers
Nicola Zerbinati, et al.
Gels, 7, 139-139 (2021)
David Stocks et al.
Journal of drugs in dermatology : JDD, 10(9), 974-980 (2011-11-05)
Hyaluronic acid (HA) gels are commonly injected into the skin to lift rhytides and to improve facial appearance. The different processes used in their manufacture and formulation yield products with unique physical characteristics that play an important role in predicting
R Zeeman et al.
Biomaterials, 20(10), 921-931 (1999-06-03)
Cross-linking of dermal sheep collagen (N-DSC, T(S) = 46 degrees C, number of amine groups = 31 (n/1000)) with 1,4-butanediol diglycidyl ether (BDDGE) at pH 9.0 resulted in a material (BD90) with a high T(S)(69 degrees C), a decreased number
Ritu Goyal et al.
Molecular bioSystems, 7(6), 2055-2065 (2011-04-21)
Previously reported 1,4-butanediol diglycidyl ether (BDE) crosslinked PEI (branched polyethylenimine, 25 k) nanoparticles (A. Swami, R. Kurupati, A. Pathak, Y. Singh, P. Kumar and K. C. Gupta, A unique and highly efficient non-viral DNA/siRNA delivery system based on PEI-bisepoxide nanoparticles
Ritu Goyal et al.
Nanomedicine : nanotechnology, biology, and medicine, 8(2), 167-175 (2011-06-28)
Linear polyethylenimine (lPEI, 25 kDa) nanoparticles' (LPN) series was synthesized by varying percentage of cross-linking with 1,4-butanediol diglycidyl ether (BDE) and their size, surface charge, morphology, pDNA protection/release, cytotoxicity and transfection efficiency were evaluated. Synthesized nanoparticles (NPs) were spherical in
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