质量水平
检测方案
≥99.0% (HPLC)
形式
solid
mp
>300 °C (lit.)
SMILES字符串
OC1=C(O)C(=O)C1=O
InChI
1S/C4H2O4/c5-1-2(6)4(8)3(1)7/h5-6H
InChI key
PWEBUXCTKOWPCW-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
一般描述
3,4-二羟基-3-环丁烯-1,2-二酮，俗称方酸，广泛用于生物有机和药物化学。它是乙二醛酶、 semiqauric acid 、丙酮酸脱氢酶和转酮醇酶的抑制剂。 它可用作SH2结构域的肽配体中磷酸盐的替代物。它的衍生物是兴奋性氨基酸受体的高亲和力配体。这些衍生物也可用作小生物分子荧光检测用染料。
应用
3,4-二羟基-3-环丁烯-1,2-二酮可用于：
- 免疫分析、杂交分析、酶促反应和其他分析过程中的荧光检测。
- 形成衍射级晶体。
- 合成方酸（squaate）二价阴离子，其可用作构建不带电聚合物网络的结构单元。这些有序的结构可用于催化、非线性光学、电导、分子识别和分子筛。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 3
闪点(°F)
374.0 °F
闪点(°C)
190 °C
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Synthesis, spectral properties, and detection limits of reactive squaraine dyes, a new class of diode laser compatible fluorescent protein labels
Oswald et al.
Bioconjugate chemistry, 11(3), 438-438 (2000-05-23)
Jian Xie et al.
Organic letters, 6(1), 83-86 (2004-01-03)
[structure: see text] Protein tyrosine phosphatases (PTPases) are important targets in medicinal chemistry. These enzymes play a role in a number of human diseases, including type II diabetes and infection by Yersinia pestis, the causative agent of bubonic plague. Derivatives
Heterocycles, 35, 1149-1149 (1993)
Igor Bensemann et al.
Organic & biomolecular chemistry, 1(8), 1425-1434 (2003-08-22)
The preparation and crystal structures of fourteen complexes of N,N'-bis(2-pyridyl)aryldiamines with dicarboxylic acids and two complexes with squaric acid are reported. The recognition between the carboxylic acids and the 2-aminopyridine units occurs through the formation of the cyclic R(2)2 (8)
Carsten Grabosch et al.
Chembiochem : a European journal of chemical biology, 12(7), 1066-1074 (2011-04-08)
Bacteria use long proteinaceous appendages, called fimbriae or pili, to adhere to the surfaces of their host cells. Widely distributed among the Enterobacteriacae are type 1 fimbriae that mediate mannose-specific bacterial adhesion through the lectin FimH, located at the fimbrial
商品
Professor Chen (Nankai University, China) and his team explain the strategies behind their recent record-breaking organic solar cells, reaching a power conversion efficiency of 17.3%.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门