119660
磷酸三(2-氯乙基)酯
97%
别名:
磷酸三（2-氯乙基）酯
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关于此项目
线性分子式:
(ClCH2CH2O)3P(O)
化学文摘社编号:
分子量:
285.49
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
204-118-5
MDL number:
Assay:
97%
InChI key
HQUQLFOMPYWACS-UHFFFAOYSA-N
InChI
1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2
SMILES string
ClCCOP(=O)(OCCCl)OCCCl
vapor pressure
<10 mmHg ( 25 °C)
assay
97%
refractive index
n20/D 1.472 (lit.)
bp
192 °C/10 mmHg (lit.)
solubility
H2O: soluble 7.82 g/L
density
1.39 g/mL at 25 °C (lit.)
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General description
磷酸三（2-氯乙基）酯在塑料中用作阻燃剂，尤其是在汽车和家具中使用的硬质泡沫以及用于建筑保温的硬质泡沫中。
Application
通过固相微萃取装置使用三（2-氯乙基）磷酸酯对空气中的有机磷酸酯进行了动态采样。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
449.6 °F - closed cup
flash_point_c
232 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
D E Chapman et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 17(2), 215-224 (1991-08-01)
Previous studies indicate that tris(2-chloroethyl)phosphate (TCP) preferentially produces hippocampal brain lesions in female versus male rats, and the expression of these lesions is inversely related to the in vivo rate of TCP metabolism. In the present studies, TCP (0.17 mM
International Commission for Protection Against Environmental Mutagens and Carcinogens. Use of SAR in computer-assisted prediction of carcinogenicity and mutagenicity of chemicals by the TOPKAT program.
K Enslein et al.
Mutation research, 305(1), 47-61 (1994-02-01)
M Sala et al.
European journal of cancer & clinical oncology, 18(12), 1337-1344 (1982-12-01)
Tris(2,3-dibromopropyl)phosphate (Tris-BP) and Tris(2-chloroethyl) orthophosphate (Genomoll P) were analyzed for mutagenic and carcinogenic activity in several in vitro and in vivo mammalian systems. In the in vitro tests both Tris-BP and Genomoll P increased sister chromatid exchanges in V79 cells
G Ingerowski et al.
Indoor air, 11(3), 145-149 (2001-08-28)
The chlorinated organo-phosphate triesters, tris(2-chloroethyl)-phosphate (TCEP) and tris(monochloroisopropyl)-phosphate (TCPP), are employed in consumer articles for indoor usage, e.g. flame retardants and plasticizers in foam material as well as in paints, varnishes and wallpapers. As a result of this widespread usage
Peter F Moore et al.
Veterinary dermatology, 24(1), 204-211 (2013-01-22)
Cutaneous T-cell lymphoma (CTCL) in dogs is a heterogeneous disease complex, which consists of nonepitheliotropic (NE) and epitheliotropic forms. These lymphomas are readily recognized by the presence of dominant populations of cytologically atypical lymphocytes. The objective of this study was
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