105481
1,3-二苯基异苯并呋喃
97%
别名:
1,3-联苯基异香豆酮, 2,5-二苯基-3,4-苯并呋喃
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关于此项目
经验公式（希尔记法）:
C20H14O
化学文摘社编号:
分子量:
270.32
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-808-5
Beilstein/REAXYS Number:
199922
MDL number:
Assay:
97%
Form:
solid
InChI key
ZKSVYBRJSMBDMV-UHFFFAOYSA-N
InChI
1S/C20H14O/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)20(21-19)16-11-5-2-6-12-16/h1-14H
SMILES string
c1ccc(cc1)-c2oc(-c3ccccc3)c4ccccc24
assay
97%
form
solid
mp
128-130 °C (lit.)
functional group
phenyl
Quality Level
General description
1,3-二苯基异苯并呋喃是一种荧光染料。1,3-二苯基异苯并呋喃是单线态裂分研究的模型化合物。
Application
1,3-二苯基异苯并呋喃(DPBF)被用作荧光探针，通过DPBF荧光淬灭法检测膜脂质层内的超氧阴离子自由基（O2−）。在含有血卟啉的TA-3小鼠乳腺癌细胞的光灭活过程中，1,3-二苯基异苯并呋喃(DPBF)被用作猝灭剂。1,3-二苯基异苯并呋喃(DPBF)曾用于研究DPBF的单晶分子结构和溶液光物理性质。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
T Ohyashiki et al.
Biochimica et biophysica acta, 1421(1), 131-139 (1999-11-16)
Utilization of a fluorescence dye, 1,3-diphenylisobenzofuran (DPBF) as a detector of superoxide anion radical (O2*-) was examined. The fluorescence intensity of DPBF incorporated in phospholipid liposomes consisting of phosphatidylcholine (PC) and phosphatidylserine (PS) is effectively quenched by incubation with xanthine/xanthine
Diana Zaharie-Butucel et al.
Journal of colloid and interface science, 552, 218-229 (2019-05-28)
Significant efforts are currently being funneled into the improvement of therapeutic outcomes in cancer by designing hybrid nanomaterials that synergistically combine chemotherapeutic abilities and near-infrared (NIR) light-activated photothermal (PTT) and photodynamic (PDT) activity. Herein, a nanotherapeutic platform is specifically designed
Xingshu Li et al.
Theranostics, 7(10), 2746-2756 (2017-08-19)
A major challenge in photodynamic therapy (PDT) is the development of new tumor-targeting photosensitizers. The tumor-specific activation is considered to be an effective strategy for designing these photosensitizers. Herein, we describe a novel tumor-pH-responsive supramolecular photosensitizer, LDH-ZnPcS
Jia Wen et al.
Scientific reports, 6, 38931-38931 (2016-12-13)
In this work, a triple-stimuli (GSH, pH and light irradiation) responsive system were designed based on CeO2 nanoparticles (CeO2 NPs) coated doxorubicin (DOX) and photosensitizer hematoporphyrin (HP) dual-loaded mesoporous silica nanoparticles (MSN). Upon entering into cancer cells, both high concentration
K R Weishaupt et al.
Cancer research, 36(7 PT 1), 2326-2329 (1976-07-01)
Singlet oxygen, a metastable state of normal triplet oxygen, has been identified as the cytotoxic agent that is probably responsible for in vitro inactivation of TA-3 mouse mammary carcinoma cells following incorporation of hematoporphyrin and exposure to red light. This
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