在线和实时拉曼监测

相关资源

• Datasheet: ProCellics™ Raman Analyzer with Bio4C^® PAT Raman Software

  Specifically designed for the bioprocessing industry, ProCellics™ Raman Analyzer with Bio4C^® PAT Raman Software enables you to perform in-line and real-time measurement of CPPs and CQAs, from process development to manufacturing.

• Article: Seamless Integration of Glucose Control in CHO Culture Using Raman Spectroscopy

  Discover opportunities of a Raman PAT platform for feedback control loop in CHO cell culture, enabling stable glucose levels without manual intervention.

• Application Note: In-line Real-time Monitoring of CHO Cell Culture Process Parameters Using Raman Spectroscopy

  Cell culture processes are complex and highly variable and yet only a handful of key parameters such as temperature, pH, and dissolved oxygen (DO) are typically controlled in real time.

• Application Note: Implementation of Raman Spectroscopy for In-line Monitoring of CPPs of CHO Cell Perfusion Cultures

  This application note introduces a case study for the implementation of a Raman spectroscopy soft-sensor for in-line and real-time monitoring of critical process parameters (CPP) in mammalian perfusion cell cultures.

• Application Note: Seamless Integration of Glucose Control Using Raman Spectroscopy in CHO Cell Cultures

  Process analytical technology (PAT) and quality by design (QbD) are used in the biopharmaceutical industry to ensure quality is designed into a process and to achieve innovative quality improvements.

• Article: Influence of Cell Specific Parameters in a Dielectric Spectroscopy Conversion Model Used to Monitor Viable Cell Density in Bioreactors

  In the biopharmaceutical industry, the use of mammalian cells to produce therapeutic proteins is becoming increasingly widespread. Monitoring of these cultures via different analysis techniques is essential to ensure a good quality product while respecting good manufacturing practice (GMP) regulations.