RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
别名:
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
物种:
Human RPS6KB1 (6198), Mouse Rps6kb1 (72508), Rat Rps6kb1 (83840), cow RPS6KB1 (404181), sheep RPS6KB1 (101107371), chicken RPS6KB1 (417637), Domestic Rabbit RPS6KB1 (100009260), domestic cat RPS6KB1 (101092561), Horse RPS6KB1 (100057481), dog RPS6KB1 (480580) ...展开
UniProtKB ID:
基因ID:
- Human(6198) Summary: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
- Mouse(72508) ribosomal protein S6 kinase, polypeptide 1
- Rat(83840) ribosomal protein S6 kinase, polypeptide 1
- cow(404181) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- sheep(101107371) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- chicken(417637) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- Domestic Rabbit(100009260) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- domestic cat(101092561) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- Horse(100057481) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- dog(480580) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- domestic guinea pig(100727216) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- naked mole-rat(101724077) ribosomal protein S6 kinase, 70kDa, polypeptide 1
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Antibodies
货号
说明
物种反应性
应用
抗磷酸-p70 S6激酶（Thr389）抗体，克隆10G7.1, clone 10G7.1, from mouse,
物种反应性
human, mouse
应用
immunocytochemistry
western blot
western blot
磷酸化p70 S6激酶（Tyr389）抗体, from rabbit, purified by affinity chromatography,
物种反应性
bovine, chicken, human, mouse, rat, zebrafish
应用
inhibition assay
western blot
western blot
Anti-S6K antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-p70 S6 Kinase (pThr389/412) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot
Anti-phospho-p70 S6 Kinase (pThr389) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
货号
说明
物种
Proteins
货号
说明
物种
p70S6K, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
p70 S6 Kinase Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase, for use in Kinase Assays.,
物种
human
p70S6K active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
物种
human
esiRNA
货号
说明
物种
