NPHS1
nephrosis 1, congenital, Finnish type (nephrin)
别名:
CNF, NPHN, nephrin
物种:
Human NPHS1 (4868), Mouse Nphs1 (54631), Rat Nphs1 (64563), Zebrafish nphs1 (692352), dog NPHS1 (484571), domestic cat NPHS1 (101101018), sheep NPHS1 (101115895), cow NPHS1 (519706), Domestic Rabbit NPHS1 (100354996), domestic guinea pig Nphs1 (100713185)
UniProtKB ID:
基因ID:
- Human(4868) Summary: This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
- Mouse(54631) nephrosis 1, nephrin
- Rat(64563) nephrosis 1, congenital, Finnish type (nephrin)
- Zebrafish(692352) nephrosis 1, congenital, Finnish type (nephrin)
- dog(484571) nephrosis 1, congenital, Finnish type (nephrin)
- domestic cat(101101018) nephrosis 1, congenital, Finnish type (nephrin)
- sheep(101115895) nephrosis 1, congenital, Finnish type (nephrin)
- cow(519706) nephrosis 1, congenital, Finnish type (nephrin)
- Domestic Rabbit(100354996) nephrosis 1, congenital, Finnish type (nephrin)
- domestic guinea pig(100713185) nephrosis 1, congenital, Finnish type (nephrin)
- naked mole-rat(101705086) nephrosis 1, congenital, Finnish type (nephrin)
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Antibodies
货号
说明
物种反应性
应用
抗 Nephrin 兔抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
抗-Nephrin抗体, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
MONOCLONAL ANTI-NEPHRIN antibody produced in mouse, clone 174CT2.1.1, crude ascites, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Monoclonal Anti-NPHS1 antibody produced in mouse, clone 3H6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot