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质量水平
方案
99%
mp
228-230 °C (lit.)
溶解性
water: soluble 1g in 1475ml(lit.)
alcohol: freely soluble(lit.)
diethyl ether: freely soluble(lit.)
hot water: soluble(lit.)
官能团
carboxylic acid
nitro
SMILES字符串
OC(=O)c1cc(ccc1O)[N+]([O-])=O
InChI
1S/C7H5NO5/c9-6-2-1-4(8(12)13)3-5(6)7(10)11/h1-3,9H,(H,10,11)
InChI key
PPDRLQLKHRZIJC-UHFFFAOYSA-N
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一般描述
2-羟基-5-硝基苯甲酸可抑制野生型牛低Mr蛋白酪氨酸磷酸酶的活性。其抑制常数已被评估。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Journal of the American Society for Mass Spectrometry, 29(7), 1473-1483 (2018-04-21)
Radical-driven dissociation (RDD) of hydrogen-deficient peptide ions [M - H + H]·+ has been examined using matrix-assisted laser dissociation/ionization in-source decay mass spectrometry (MALDI-ISD MS) with the hydrogen-abstracting matrices 4-nitro-1-naphthol (4,1-NNL) and 5-nitrosalicylic acid (5-NSA). The preferential fragment ions observed in the ISD spectra
Biochemistry, 38(9), 2636-2646 (1999-03-03)
Pyridoxal 5'-phosphate (PLP) binds tightly to bovine low Mr protein tyrosine phosphatase (BPTP), but it is a very poor substrate for the enzyme. The structural basis of this tight binding of PLP is examined here by a variety of methods.
Free radical biology & medicine, 108, 715-724 (2017-05-06)
Mesalazine (5-aminosalicylic acid, 5-ASA), a currently used drug for anti-inflammatory bowel disease, is easily oxidized by HOCl, a strong oxidant generated in gut inflammation, to produce electrophilic quinones. We investigated whether this chemical feature has an implication in the anti-inflammatory
MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation.
Proceedings of the National Academy of Sciences of the United States of America, 112(32), 9978-9983 (2015-07-29)
We present a proof of concept study designed to support the clinical development of mass spectrometry imaging (MSI) for the detection of pituitary tumors during surgery. We analyzed by matrix-assisted laser desorption/ionization (MALDI) MSI six nonpathological (NP) human pituitary glands
Rapid communications in mass spectrometry : RCM, 34(10), e8722-e8722 (2020-01-09)
Hyphenation of atmospheric pressure chemical ionization (APCI) mass spectrometry with capillary and micro high-performance liquid chromatography (HPLC) is attractive for many applications, but reliable ion sources dedicated to these conditions are still missing. There are a number of aspects to
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