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质量水平
检测方案
99%
mp
228-230 °C (lit.)
溶解性
water: soluble 1g in 1475ml(lit.)
alcohol: freely soluble(lit.)
diethyl ether: freely soluble(lit.)
hot water: soluble(lit.)
SMILES字符串
OC(=O)c1cc(ccc1O)[N+]([O-])=O
InChI
1S/C7H5NO5/c9-6-2-1-4(8(12)13)3-5(6)7(10)11/h1-3,9H,(H,10,11)
InChI key
PPDRLQLKHRZIJC-UHFFFAOYSA-N
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一般描述
2-羟基-5-硝基苯甲酸可抑制野生型牛低Mr蛋白酪氨酸磷酸酶的活性。其抑制常数已被评估。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Keishiro Nagoshi et al.
Journal of the American Society for Mass Spectrometry, 29(7), 1473-1483 (2018-04-21)
Radical-driven dissociation (RDD) of hydrogen-deficient peptide ions [M - H + H]·+ has been examined using matrix-assisted laser dissociation/ionization in-source decay mass spectrometry (MALDI-ISD MS) with the hydrogen-abstracting matrices 4-nitro-1-naphthol (4,1-NNL) and 5-nitrosalicylic acid (5-NSA). The preferential fragment ions observed in the ISD spectra
Sookjin Kang et al.
Free radical biology & medicine, 108, 715-724 (2017-05-06)
Mesalazine (5-aminosalicylic acid, 5-ASA), a currently used drug for anti-inflammatory bowel disease, is easily oxidized by HOCl, a strong oxidant generated in gut inflammation, to produce electrophilic quinones. We investigated whether this chemical feature has an implication in the anti-inflammatory
MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation.
David Calligaris et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(32), 9978-9983 (2015-07-29)
We present a proof of concept study designed to support the clinical development of mass spectrometry imaging (MSI) for the detection of pituitary tumors during surgery. We analyzed by matrix-assisted laser desorption/ionization (MALDI) MSI six nonpathological (NP) human pituitary glands
Timotej Strmeň et al.
Rapid communications in mass spectrometry : RCM, 34(10), e8722-e8722 (2020-01-09)
Hyphenation of atmospheric pressure chemical ionization (APCI) mass spectrometry with capillary and micro high-performance liquid chromatography (HPLC) is attractive for many applications, but reliable ion sources dedicated to these conditions are still missing. There are a number of aspects to
Assala Lamaa et al.
eLife, 9 (2020-02-29)
The H2A.Z histone variant plays major roles in the control of gene expression. In human, H2A.Z is encoded by two genes expressing two isoforms, H2A.Z.1 and H2A.Z.2 differing by three amino acids. Here, we undertook an integrated analysis of their
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