WT1
Wilms tumor 1
别名:
AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
物种:
Human WT1 (7490), Mouse Wt1 (22431), Rat Wt1 (24883), domestic guinea pig Wt1 (100716139), dog WT1 (609253), sheep WT1 (100101227), naked mole-rat Wt1 (101714640), cow WT1 (280959), chicken WT1 (396139), cow WT1 (782183) ...展开
UniProtKB ID:
基因ID:
- Human(7490) Summary: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
- Mouse(22431) Wilms tumor 1 homolog
- Rat(24883) Wilms tumor 1
- domestic guinea pig(100716139) Wilms tumor 1
- dog(609253) Wilms tumor 1
- sheep(100101227) Wilms tumor 1
- naked mole-rat(101714640) Wilms tumor 1
- cow(280959) Wilms tumor 1
- chicken(396139) Wilms tumor 1
- cow(782183) Wilms tumor 1
- cow(614584) Wilms tumor 1
- domestic cat(101088518) Wilms tumor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
抗-WT1抗体，克隆6F-H2, clone 6F-H2, Upstate®, from mouse,
物种反应性
human
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-肾母细胞′瘤抗体，NT，克隆6F-H2, clone 6F-H2, Chemicon®, from mouse,
物种反应性
human, mouse
应用
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-WT1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
抗Wilms′瘤抗体，NT，克隆6F-H2，无腹水, clone 6F-H2, from mouse,
物种反应性
human, mouse
应用
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-WT1, affinity isolated antibody,
物种反应性
dog, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Proteins
esiRNA
货号
说明
物种