SOCS3
suppressor of cytokine signaling 3
别名:
ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3
物种:
Human SOCS3 (9021), Mouse Socs3 (12702), Rat Socs3 (89829), sheep SOCS3 (100294595), domestic guinea pig Socs3 (100725088), naked mole-rat Socs3 (101704157), chicken SOCS3 (395299), dog SOCS3 (442949), Horse SOCS3 (100050730), domestic cat SOCS3 (101081846)
UniProtKB ID:
基因ID:
- Human(9021) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
- Mouse(12702) suppressor of cytokine signaling 3
- Rat(89829) suppressor of cytokine signaling 3
- sheep(100294595) suppressor of cytokine signaling 3
- domestic guinea pig(100725088) suppressor of cytokine signaling 3
- naked mole-rat(101704157) suppressor of cytokine signaling 3
- chicken(395299) suppressor of cytokine signaling 3
- dog(442949) suppressor of cytokine signaling 3
- Horse(100050730) suppressor of cytokine signaling 3
- domestic cat(101081846) suppressor of cytokine signaling 3
- cow(282081) suppressor of cytokine signaling 3
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Antibodies
货号
说明
物种反应性
应用
Anti-SOCS3 Antibody, clone 1B2, clone 1B2, Upstate®, from mouse,
物种反应性
human, mouse
应用
western blot
Anti-SOCS-3 Antibody, clone 2N6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-SOCS3 antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Monoclonal Anti-SOCS3 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
immunofluorescence